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Dobberstein, J.; Tamaschke, Ch.

doi:10.1007/978-3-662-28339-4_39

Cited by 4 publications

(2 citation statements)

References 147 publications

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“…9,23 Polypoid adenomas of the intestinal mucosa and adenocarcinomas, most commonly in the large intestine, have been described. 5,30 Myxomas, myxofibromas, leiomyomas, neurofibromas, and hemangiomas have been occasionally reported, 3,4,8,20,21,26,28 and the morphology of some of these are similar to that of the GIST in the present study. Three of the GIST included in this study were found following the examination of a population of 400 mainly mature horses in which three gastric squamous cell carcinomas and one colon leiomyosarcoma were also identified.…”

Section: Discussionsupporting

confidence: 65%

Gastrointestinal Stromal Tumors in Equids

et al. 2001

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Abstract. Eleven gastrointestinal neoplasms from 10 aged horses and 1 pony were examined grossly, histologically, immunohistochemically, and (in two cases) ultrastructurally. Clinical signs were associated with two neoplasms, and the other nine tumors were incidental findings at laparotomy or necropsy. The neoplasms were solitary (9/11) or multifocal (2/11), well demarcated, serosal or mural masses of stomach (1), jejunum (1), ileum (3), cecum (5), and/or colon (2). Microscopic examination revealed discrete spindle cells arranged in compact patterns with fascicles and whorls or cribriform pattern with fascicles and rare palisades, often with a myxoid interstitial matrix. Three tumors infiltrated between the muscularis interna and the muscularis externa at the myenteric plexi. All neoplasms were vimentin positive, 3/11 were S-100 positive, 2/11 were muscle actin positive, and no neoplasm was positive for glial fibrillary acid protein, desmin, factor VIII, chromogranin, or neuron-specific enolase. Of the two tumors studied ultrastructurally, one contained an admixture of smooth muscle cells and cells resembling Schwann cells, and the second was populated by homogeneous fusiform mesenchymal cells separated by homogeneous matrix. Gastrointestinal stromal tumors (GIST) have been recognized in humans, more recently in dogs and nonhuman primates, and now in equids. Most of these tumors are comprised of a loosely arranged network of spindled cells separated by myxoid matrix. GIST may be composed of myogenic, neurogenic, combined myogenic and neurogenic, and undifferentiated mesenchymal cells.

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Section: Discussionsupporting

confidence: 65%

Gastrointestinal Stromal Tumors in Equids

et al. 2001

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“…In an older compilation of case reports on rabbit neoplasms, embryonal nephroma was described with the second highest frequency next to uterine carcinoma. 26 However, this does not equal a high prevalence, because an uncommon neoplasm has a higher likelihood of publication than a well-known one.…”

Section: Urinary Tractmentioning

confidence: 99%

Not Just Uterine Adenocarcinoma—Neoplastic and Non-Neoplastic Masses in Domestic Pet Rabbits (Oryctolagus cuniculus): A Review

Baum

2021

Vet Pathol

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With increasing numbers of pet rabbits living out their natural lifespan, rabbit oncology is stepping more and more into the limelight. On the other hand, rabbit tumors are less covered in recent editions of textbooks of veterinary pathology than before. We present 1238 cases with neoplastic and non-neoplastic masses in rabbit tissue, submitted from 2008 to 2019, supplemented by a review of the literature on neoplasms in rabbits. Cutaneous masses comprised 47% of submissions. Trichoblastoma was by far the most common skin neoplasm, and nodular suppurative panniculitis was the second most frequent skin nodule in this series. Epithelial as well as mesenchymal cutaneous neoplasms can be virally induced in rabbits (eg, Shope papilloma, myxomatosis) but were infrequent in the current cases. Mammary neoplasms comprised 21% of submitted masses and 94% of these had histologic features of malignancy. Tumors of the female reproductive tract were responsible for 9% of biopsies and were predominantly uterine adenocarcinoma. Polypoid proliferation of rectal mucosa was the most common lesion in the alimentary tract. A broad spectrum of other neoplasms was described, including sarcomas at vaccination sites and ocular posttraumatic sarcomas, comparable to lesions described in cats.

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Experimenteller Krebs

Kimmig

Jänner

1969

Nicht Entzündliche Dermatosen II

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Tumoren

Cited by 4 publications

References 147 publications

Gastrointestinal Stromal Tumors in Equids

Gastrointestinal Stromal Tumors in Equids

Not Just Uterine Adenocarcinoma—Neoplastic and Non-Neoplastic Masses in Domestic Pet Rabbits (Oryctolagus cuniculus): A Review

Experimenteller Krebs

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