2008
DOI: 10.2967/jnumed.108.051649
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Tumor Volume Assessment by18F-FDG PET/CT in Patients with Oral Cavity Cancer with Dental Artifacts on CT or MR Images

Abstract: The purpose of this study was to investigate the clinical usefulness of PET/CT or CT-attenuated PET in the evaluation of patients with oral cavity cancer (OCC) in whom dental artifacts distorted the conventional CT or MR images of the oral cavity. Methods: A PET/CT scan, in addition to a CT or MRI scan, was performed in 69 patients with OCC who had dentures or dental implants. A total of 64 PET/CT, 64 CT, and 27 MR images were analyzed including images from scans performed on 40 patients with OCC without denta… Show more

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Cited by 56 publications
(38 citation statements)
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References 27 publications
(46 reference statements)
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“…On the other hand, it was difficult to identify musculature, major vessels including the carotid artery and jugular vein, and maxillary sinuses, which were readily delineated in the same subjects with the use of CT and MRI. The utility of FDG-PET/CT for diagnosing head and neck cancers has been reported, and it was found that the method shows both anatomical and functional images simultaneously (15,16). Additional investigations of PET/CT with fluoridelabeled BPA as a tracer are warranted, not only for improving the diagnostic potential, but also for treatment planning.…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, it was difficult to identify musculature, major vessels including the carotid artery and jugular vein, and maxillary sinuses, which were readily delineated in the same subjects with the use of CT and MRI. The utility of FDG-PET/CT for diagnosing head and neck cancers has been reported, and it was found that the method shows both anatomical and functional images simultaneously (15,16). Additional investigations of PET/CT with fluoridelabeled BPA as a tracer are warranted, not only for improving the diagnostic potential, but also for treatment planning.…”
Section: Discussionmentioning
confidence: 99%
“…In contrast, our data are based on the combined measurement of metabolically active tumor burden and glucose utilization in these lesions. Of note, studies in oral cavity and larynx cancer have shown that tumor volume derived from 18 F-FDG PET/CT data correlates better with gross pathology volume than volumes measured on CT or MRI (24,25).…”
Section: Multivariate Analysismentioning
confidence: 99%
“…Multidetector computed tomography (CT) is among the most important examinations when diagnosing and staging oral and oropharyngeal cancers [2,3]. Tumor enhancement and the degree of mass effect on contrast-enhanced CT imaging reportedly correlate with genomic biomarkers that are potential drug targets [4].…”
Section: Introductionmentioning
confidence: 99%