Tumor-treating fields dosimetry in glioblastoma: Insights into treatment planning, optimization, and dose–response relationships
Nikola Mikic,
Nichal Gentilal,
Fang Cao
et al.
Abstract:Tumor Treating Fields (TTFields) is currently a Category 1A treatment recommendation by the U.S. National Comprehensive Cancer Center for patients with newly diagnosed glioblastoma. Although the mechanism of action of TTFields has been partly elucidated, tangible and standardized metrics are lacking to assess anti-tumor dose and effects of the treatment. This paper outlines and evaluates the current standards and methodologies in the estimation of the TTFields distribution and dose measurement in the brain and… Show more
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