Tumor Staging of Advanced Esophageal Cancer: Combination of Double-Contrast Esophagography and Contrast-Enhanced CT

Yamabe, Yuichiro; Kuroki, Yoshio; Ishikawa, Tsutomu; Miyakawa, Kunihisa; Kuroki, Seiko; Sekiguchi, Ryuzo

doi:10.2214/ajr.07.3581

Cited by 24 publications

(17 citation statements)

References 18 publications

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“…The chemotherapeutic regimens included two courses of chemotherapy of cisplatin (CDDP; 80 mg/m 2 of intravenous drip infusion, day 1) and 5-fluorouracil (5-FU; 800 mg/m 2 of continuous infusion, days [1][2][3][4][5]. For the chemoradiotherapy, the chemotherapeutic regimens included the administration of CDDP (70 mg/m 2 of intravenous drip infusion, day 1) and 5-FU (700 mg/m 2 of continuous infusion, days [1][2][3][4], and the concurrent radiation therapy was planned to be administered in daily fractions of 2 Gy for a total dose of 30-40 Gy (median 30.9).…”

Section: Methodsmentioning

confidence: 99%

“…For the chemoradiotherapy, the chemotherapeutic regimens included the administration of CDDP (70 mg/m 2 of intravenous drip infusion, day 1) and 5-FU (700 mg/m 2 of continuous infusion, days [1][2][3][4], and the concurrent radiation therapy was planned to be administered in daily fractions of 2 Gy for a total dose of 30-40 Gy (median 30.9). The chemotherapy or chemoradiotherapy as an induction therapy was chosen, taking risk and benefit into consideration.…”

Section: Methodsmentioning

confidence: 99%

“…As the esophagus is not surrounded by a serosal lining, infiltration into adjacent mediastinal structures, including the aorta, tracheobronchial tree and vertebral column, occurs easily (3). It is extremely important to accurately evaluate tumor invasion of the adjacent mediastinal structures in order to prevent unnecessary surgery in patients with inoperable tumors (4,5).…”

Section: Introductionmentioning

confidence: 99%

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Multidetector-computed tomography attenuation values between the tumor and aortic wall in response to induction therapy for esophageal cancer and its predictive value for aortic invasion

Tsujimoto

Ichikura

Aiko

et al. 2011

Experimental and Therapeutic Medicine

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Abstract. The objective of this study was to evaluate the multidetector computed tomography (MDCT) attenuation value between the tumor and aorta in response to the induction therapy for esophageal cancer. In advanced esophageal cancer, the main reason for unresectability is the local invasion of the tumor into the aorta or trachea. Despite remarkable advances in diagnostic modalities, pre-operative assessment of pathological response and local tumor extent in esophageal cancer remains difficult. MDCT attenuation values between the tumor and aorta, and the contact angle of the tumor to the aorta (Picus' angle) were retrospectively evaluated in patients with esophageal cancer who underwent induction therapy in terms of predicting the pathological response, aortic invasion and prognosis of esophageal cancer. The induction therapy may increase the tumor-to-aorta distance and decrease the maximum tumor size and Picus' angle. When the tumor-to-aorta cut-off value was set at <1.3 mm, the accuracy of this distance for aortic invasion was 94.6%. In terms of this distance, 14 out of 19 patients with a tumor-to-aorta distance of <1.3 mm prior to the induction therapy had a distance of >1.3 mm following therapy and underwent curative resection. The assessment of the MDCT attenuation value between the esophageal tumor and the aorta is simple and objectively assesses the response to the induction therapy and aortic invasion in esophageal cancer. This method should be applied to predict the response to the induction therapy and to prevent unnecessary surgery in patients with tumors involving the aorta.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Multidetector-computed tomography attenuation values between the tumor and aortic wall in response to induction therapy for esophageal cancer and its predictive value for aortic invasion

Tsujimoto

Ichikura

Aiko

et al. 2011

Experimental and Therapeutic Medicine

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show abstract

“…The use of CT has continuously increased due to latest applications and the demand for better technology. 1 For the last few years, rapid technological advances in cross-sectional imaging modalities have combined with increased number of scanners to enable multiple new modes of imaging the oesophageal carcinoma. Radiologists are skilled in interpreting CT scans in the axial plane, but the development of MDCT coupled with faster reconstruction hardware and software has piqued deep interest in viewing the oesophagus planes other than the axial plane.…”

Section: Introductionmentioning

confidence: 99%

CT imaging and staging of carcinoma oesophagus

et al. 2017

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Background: Over the past decades, computerized tomography (CT) technology has led to an early detection of cancers and thereby decreasing mortality rate. The objective was to demonstrate usefulness of Toshiba Activion 16 slice multi detector computerized tomography (MDCT) scan in staging of oesophageal cancer.Methods: The study was carried out in the Department of Radio diagnosis, Bapuji Hospital and Chigateri Government Hospital attached to Jagadguru Jayadeva Murugarajendra Medical College, Davangere, Karnataka, India over a period of 24 months. After taking a properly informed written consent, complete history and thorough clinical examination was done and these patients were subjected to CT scan.Results: The total numbers of patients studied in present study were 25. Out of which 10 were males and 15 were females. There were 6 patients upto the age of 54 years and 8 patients equal to or greater than 65 years of age, there were 11 patients between 55-64 years of age. Dysphagia was the most common symptom in patients and was present in all the 25 patients of present study. Other common symptoms were weight loss followed by pain in throat. Two different types of wall thickenings of the involved portion have been reported. The most common asymmetrical wall thickening was observed in maximum number of patients 18 (72%) and circumferential wall thickening was observed only in 7 number (28%) of patients out of 25 total patients showing heterogeneous/homogeneous enhancement. Lower third (40%) and middle third (40%) of the esophagus was the most common site of involvement with regards to location of oesophageal cancer followed by upper third (20%) of the esophagus. Homogeneous wall attenuation was observed in most of the cases accounting for (64%). The other type of wall attenuation noted were heterogeneous (36%).Conclusions: By performing endoscopy uncertainty lies in discrimination of muscular layer from serosal layer in most parts of esophagus. However, by employing MDCT technique separation of 2 layers of esophagus can be better judged. Therefore, MDCT has been found to be the most valuable and preferential technique for planning operational strategy.

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“…As the esophagus does not have an outer serosa, infiltration into adjacent mediastinal structures, including the aorta, tracheobronchial tree, and vertebral column, occurs readily. Despite remarkable advances in the various diagnostic modalities, the preoperative assessment of local tumors in esophageal cancer is still remarkably difficult …”

Section: Introductionmentioning

confidence: 99%

Distance between the esophageal tumor and the aorta measured by using the contrast‐enhanced attenuation on computed tomography for predicting this tumor invading aorta

Tsujimoto

Matsumoto

Kumano

et al. 2013

J of Gastro and Hepatol

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Tumor Staging of Advanced Esophageal Cancer: Combination of Double-Contrast Esophagography and Contrast-Enhanced CT

Abstract: The diagnostic performance of contrast-enhanced CT and double-contrast esophagography combined in staging advanced esophageal tumors is better than that of CT alone and thus has potential for estimating prognosis.

Cited by 24 publications

References 18 publications

Multidetector-computed tomography attenuation values between the tumor and aortic wall in response to induction therapy for esophageal cancer and its predictive value for aortic invasion

Multidetector-computed tomography attenuation values between the tumor and aortic wall in response to induction therapy for esophageal cancer and its predictive value for aortic invasion

CT imaging and staging of carcinoma oesophagus

Distance between the esophageal tumor and the aorta measured by using the contrast‐enhanced attenuation on computed tomography for predicting this tumor invading aorta

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