Tumor shape pulmonary mucormycosis associated with sinonasal aspergillosis in a diabetic patient

Point, Sophie; Gabriel, Frédéric; Bégueret, Hugues; Jougon, Jacques; Grenouillet, F.; Fattah, Manal Abdel; Catherinot, Émilie; Blanchard, Élodie

doi:10.1016/j.mmcr.2017.08.001

Cited by 10 publications

(14 citation statements)

References 22 publications

(25 reference statements)

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“…In the present study, the general symptoms and signs of the patients in descending order consisted of oedema, ptosis, facial pain, headache, blindness, nasal discharge, a decrease in facial sensation, nausea and vomiting, visual deficiency, ptosis, fever and nasal necrosis; the oral manifestations in these patients consisted of palatal necrosis, palatal ulcers, aphthous and lesions on the tongue, respectively (Table ). The clinical symptoms include fever, malaise, headache, pain in the orbital area, sinusitis, sudden loss of vision, proptosis, ptosis, diplopia, nasal discharge and facial anesthesia . The incidence of fever is variable and not be seen in half of the patients …”

Section: Discussionmentioning

confidence: 99%

“…In the present study, the mortality rate was estimated at 42.5% in 40 patients over a period of >10 years, which is comparable to global statistics (Table ). The mortality rate of mucormycosis depends on the clinical manifestations, background factors, surgery and the extension of infection . Ambrosioni et al in a retrospective study of 55 patients of invasive mucormycosis reported a mortality rate of 75% for cases that were treated only with antifungal agents and 14% for cases treated with a combination of surgery and antifungal agents .…”

Section: Discussionmentioning

confidence: 99%

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Rhinocerebral mucormycosis, risk factors and the type of oral manifestations in patients referred to a University Hospital in Tabriz, Iran 2007‐2017

Nezafati

Kazemi

Asgari

et al. 2018

Mycoses

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Inadequate data are available on the global epidemiology of mucormycosis, mainly derived from the evaluation of specific population groups. Rhinocerebral mucormycosis is an invading and fatal mycosis, particularly among diabetic patients. In the present study, patients hospitalised in Imam Reza Hospital in Tabriz, from 2007 to 2017, were evaluated. The hospital information system (HIS) was used to collect the records of the patients. A total of 42 patients with a diagnosis of mucormycosis were included in the study, 40 cases (95%) of which had a diagnosis of the rhinocerebral form. Of these 40 patients, 21 (52.5%) and 19 (47.5%) were male and female, respectively. Seven cases (17.5%) of rhinocerebral mucormycosis were due to dental procedures. The most predisposing factor in the patients was diabetes with 36 (90%) cases. In our study, the role of tooth extraction in patients with uncontrolled diabetes was identified as an important factor. It may show the important role of dentists in preventing of the disease in diabetic patients.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Rhinocerebral mucormycosis, risk factors and the type of oral manifestations in patients referred to a University Hospital in Tabriz, Iran 2007‐2017

Nezafati

Kazemi

Asgari

et al. 2018

Mycoses

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“…Inhalation of ubiquitous spores is the main mode of infection. There is no evidence of human to human transmission [8]. Recent reclassification has abolished the class zygomycetes, and hence, the term zygomycosis is inappropriate for use, although it may still be used to address mucormycosis [1].…”

mentioning

confidence: 99%

Pulmonary Mucormycosis: A Case Report of a Rare Infection with Potential Diagnostic Problems

Mekki

Hassan

Falemban

et al. 2020

Case Reports in Pathology

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Pulmonary mucormycosis is a relatively rare pulmonary fungal disease, which is difficult to diagnose early and lacks effective treatment. It is seen in patients with hematological malignancies, diabetes mellitus, and immunocompromised states. The diagnosis depends primarily on the detection of fungi in lung tissue. Here, we present a case of a 52-year-old male who has type 2 diabetes mellitus and a past history of treated pulmonary tuberculosis. Clinical diagnosis is difficult in pulmonary mucormycosis, and early diagnosis is needed for this life-threatening infection. Histopathological examination of a resected cavity confirmed the diagnosis of pulmonary mucormycosis. This report highlights the difficulty of diagnosis and the importance of histological examination in detecting mucormycosis which will help for early management.

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“…The most commonly found genera in human infections are Rhizopus , Mucor , and Rhizomucor . Their broad and irregular hyphae infect humans by inhalation of spores [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

Pulmonary Mucormycosis in a Poorly Controlled Diabetic Patient

Duarte¹,

Tiago²,

Camble³

et al. 2022

Cureus

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Mucormycosis is a severe fungal infection that occurs mainly in immunocompromised patients. It is characterized by several syndromes with rhino-orbito-cerebral and pulmonary involvement. We report the case of a 49-year-old patient admitted for diabetic ketoacidosis and Influenza B pneumonia nonresponsive to treatment, which was later diagnosed with pulmonary mucormycosis. After correct diagnosis and appropriate treatment with isavuconazole, the patient had a favorable evolution, which reinforces the importance of an accurate diagnosis.

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Tumor shape pulmonary mucormycosis associated with sinonasal aspergillosis in a diabetic patient

Cited by 10 publications

References 22 publications

Rhinocerebral mucormycosis, risk factors and the type of oral manifestations in patients referred to a University Hospital in Tabriz, Iran 2007‐2017

Rhinocerebral mucormycosis, risk factors and the type of oral manifestations in patients referred to a University Hospital in Tabriz, Iran 2007‐2017

Pulmonary Mucormycosis: A Case Report of a Rare Infection with Potential Diagnostic Problems

Pulmonary Mucormycosis in a Poorly Controlled Diabetic Patient

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