1999
DOI: 10.1080/10590509909373507
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Tumor profiles and carcinogenic potency in rodents and humans: Value for cancer risk assessment

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Cited by 11 publications
(1 citation statement)
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“…When considering the prediction of mutagenicity and carcinogenicity, we have generally been considering the results from the rodent assay. It is accepted that the rodent assay is a satisfactory method to identify whether or not a chemical may be carcinogenic to humans, even if it is not possible to extrapolate with certainty specific tumor responses [49]. It should, therefore, be possible to extrapolate carcinogenic potency to predict the effects on ecologically relevant species.…”
Section: Introductionmentioning
confidence: 99%
“…When considering the prediction of mutagenicity and carcinogenicity, we have generally been considering the results from the rodent assay. It is accepted that the rodent assay is a satisfactory method to identify whether or not a chemical may be carcinogenic to humans, even if it is not possible to extrapolate with certainty specific tumor responses [49]. It should, therefore, be possible to extrapolate carcinogenic potency to predict the effects on ecologically relevant species.…”
Section: Introductionmentioning
confidence: 99%