Tumor‐On‐A‐Chip Models for Predicting In Vivo Nanoparticle Behavior
Kim E. de Roode,
Khadijeh Hashemi,
Wouter P. R. Verdurmen
et al.
Abstract:Nanosized drug formulations are broadly explored for the improvement of cancer therapy. Prediction of in vivo nanoparticle (NP) behavior, however, is challenging, given the complexity of the tumor and its microenvironment. Microfluidic tumor‐on‐a‐chip models are gaining popularity for the in vitro testing of nanoparticle targeting under conditions that simulate the 3D tumor (microenvironment). In this review, following a description of the tumor microenvironment (TME), the state of the art regarding tumor‐on‐a… Show more
Metal ion interference therapy (MIIT) has emerged as a promising approach in the realm of nanomedicine for combatting cancer. With advancements in nanotechnology and tumor targeting-related strategies, sophisticated nanoplatforms have...
Metal ion interference therapy (MIIT) has emerged as a promising approach in the realm of nanomedicine for combatting cancer. With advancements in nanotechnology and tumor targeting-related strategies, sophisticated nanoplatforms have...
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