2015
DOI: 10.4078/jrd.2015.22.5.293
|View full text |Cite
|
Sign up to set email alerts
|

Tumor Necrosis Factor-α Gene Signature Is Absent in Peripheral Blood Mononuclear Cells of Patients with Granulomatosis Polyangiitis

Abstract: Objective. Granulomatosis with polyangiitis (GPA), formally known as Wegener's granulomatosis, is a systemic vasculitis with necrotizing granulomatous inflammation. As treatment directed against tumor necrosis factor (TNF)-α failed in GPA, we investigated whether "TNF-α signature" (i.e. gene expression profile of TNF-α activation) was present in peripheral blood mononuclear cells (PBMCs) of patients with GPA. Methods. Gene expression profiling was performed using total RNA from PBMCs of 41 patients with GPA an… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 26 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?