Tumor lysis syndrome in a patient with ovarian yolk sac tumor

Abstract

HighlightsTumor lysis syndrome is an oncologic emergency with profound metabolic derangements.Germ cell tumors with large disease burden increase the risk for tumor lysis syndrome.Herein we present a case of tumor lysis syndrome prior to initiation of cytotoxic chemotherapy for ovarian yolk sac tumor.

Advanced ovarian cancer that resulted in death from intestinal perforation following tumor lysis syndrome: A case report

“…Since 1993, seven cases of TLS in ovarian cancer have been reported ( Table 1 ) [6] , [7] , [8] , [9] , [10] , [11] , [12] . TLS has occurred regardless of histological type or chemotherapeutic drugs, with every case having a high-volume tumor.…”

Clinical Features, Treatment, and Outcome of Tumor Lysis Syndrome in Germ Cell Tumors

“…Systematic review of the literature was performed by searching PubMed for "germ cell tumor", "testicular cancer", "ovarian cancer", and "tumor lysis syndrome". The identified case studies were reviewed [11][12][13][14][15][16][17][18][19][20][21][22].…”

Tumor lysis syndrome in gynecologic cancers: An uncommon but important diagnosis to recognize

“…TLS has not been comprehensively described in gynecologic cancers (Hiraizumi et al, 2011, Weed et al, 2003, Godoy et al, 2010, Yahata et al, 2006, Baeksgaard and Sorensen, 2003, Okamoto et al, 2015, Berger et al, 2017, Alaigh and Datta, 2017, Shukla et al, 2017, VanHise et al, 2017). Data for solid malignancies rely on case reports.…”

“…Followed by breast (13 cases), then gynecologic cancers (10 cases) (Mirrakhimov et al, 2014). Table 2 demonstrates the most recent 13 reported cases of TLS associated with a gynecologic malignancy (Hiraizumi et al, 2011, Chan et al, 2005, Camarata et al, 2013, Godoy et al, 2010, Yahata et al, 2006, Baeksgaard and Sorensen, 2003, Okamoto et al, 2015, Berger et al, 2017, Alaigh and Datta, 2017, Shukla et al, 2017, VanHise et al, 2017). TLS was most commonly associated with ovarian or uterine cancers and occurred at the time of new diagnosis or recurrence [Table 2].…”