Tumor-Like Growth of Giant Inflammatory Polyposis in a Patient with Ulcerative Colitis

Nagashima, Makoto; Sugishita, Yui; Moriyama, Ayako; Ooshiro, Mitsuru; Kadoya, Kengo; Sato, Ayami; Kitahara, Tomoaki; Takagi, Ryuichi; Urita, Tasuku; Yoshida, Yutaka; Tanaka, Hiroshi; Oshiro, Takashi; Nakamura, Kentaro; Suzuki, Yasuo; Hiruta, Nobuyuki; Okazumi, Shinichi; Katoh, Ryoji

doi:10.1159/000354974

Cited by 16 publications

(16 citation statements)

References 14 publications

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“…Inflammatory filiform polyps in the colon of patients with ulcerative colitis have been first reported by Appelman et al ( 8 ) in 1974. The incidence of inflammatory polyps has been reported to be 10%-20% in both ulcerative colitis and Crohn’s disease ( 5 ). It has been postulated that these polyps develop in patients with ulcerative colitis and Crohn’s disease due to regeneration of mucosa during remission after recurrent acute inflammation ( 5 ).…”

Section: Discussionmentioning

confidence: 99%

“…The incidence of inflammatory polyps has been reported to be 10%-20% in both ulcerative colitis and Crohn’s disease ( 5 ). It has been postulated that these polyps develop in patients with ulcerative colitis and Crohn’s disease due to regeneration of mucosa during remission after recurrent acute inflammation ( 5 ). Moreover, these polyps have been determined as the asymptomatic sequela of ulcerative colitis in clinicopathologic and immunophenotypic examinations ( 1 ).…”

Section: Discussionmentioning

confidence: 99%

“…Although adult cases of filiform polyposis have been reported in the literature ( 1 , 3 , 4 , 5 ), there are only a few pediatric cases of inflammatory bowel disease with filiform polyposis ( 6 , 7 ). We report a case of a 15-year-old girl with ulcerative colitis who had filiform polyposis.…”

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Filiform Polyposis in Ulcerative Colitis: A Rare Pediatric Case

2018

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Background:Filiform polyposis is a rare benign condition referred to as inflammatory polyposis, or pseudopolyposis that is usually found in association with Crohn’s disease, ulcerative colitis or granulomatous colitis which is formed by non-specific mucosal and submucosal reactions to previous severe inﬂammation. It is characterized by multiple finger-like projections most commonly in the transverse and descending colon.Case Report:A 15-year-old girl with a history of ulcerative colitis was admitted to the pediatric emergency department with abdominal pain attacks for the past 2 weeks. Abdominal ultrasound and magnetic resonance enterography revealed mucosal thickening in the transverse and descending colon. Colonoscopy revealed small filiform polyps throughout the colon. Histopathological examination revealed inflammatory polyps associated with ulcerative colitis.Conclusion:Non-neoplastic filiform polyps can be detected even in children with ulcerative colitis with long-term remissions.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Filiform Polyposis in Ulcerative Colitis: A Rare Pediatric Case

2018

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“…Presence of mainly numerous filamentous polyps projecting above the surrounding mucosa is called filiform polyposis. These polyps are associated with crohn's disease in approximately twothirds of cases and with UC in one-third of cases [4].…”

Section: Discussionmentioning

confidence: 99%

Extensive Giant Inflammatory Pseudopolyposis in Ulcerative Colitis

Bansal¹,

Farooq²

2017

J Hepatol Gastroint Dis

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Giant Inflammatory pseudo polyposis are rare complications seen usually in inflammatory bowel disease. We report a case of extensive giant inflammatory pseudo-polyposis in a 48 year old male with long standing history of ulcerative colitis (UC). His colonoscopy revealed large polypoidal mass in colon. He underwent procto-colectomy with ileal pouch anastomosis. Colectomy specimen revealed extensive circumferential polyposis (>500) filling the entire colon which on histology showed inflammatory polyps. This case highlights extensive polyposis disease in a long standing case of UC masquerading as a neoplasm. Keywords: Giant inflammatory pseudopoluposis; Ulcerative colitis Case ReportA 48 year old male from Afghanistan diagnosed as ulcerative colitis in 2000. He did not receive any specific treatment till 2015. Patient presented in April 2015 with diarrhoea and blood in the stools. He underwent colonoscopy which revealed pancolitis. He was put on ASA, Azathioprine and steroids. Patient came for a follow-up in May 2016. He was having non bloody stools 3-4 episodes/day which were semisolid. He was not able to taper his steroids dose below 20 mg/day. There was no history of abdominal pain. He underwent colonoscopy which revealed a large polypoidal lesion with smooth surface occupying the entire lumen of the colon. Numerous small polyps were seen in rectum. Colonoscope could not be negotiated through the growth. Biopsy taken for histopathology revealed inflammatory polyp. Patient underwent procto-colectomy with ileal pouch anal anastomosis. Gross examination of specimen revealed more than five hundred polyps filling the entire colon and rectum. Histology from these polyps show benign inflammatory pseudopolyposis.

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“…However, patients may present with a variety of symptoms, including anemia, weight loss, cramping abdominal pain, and diarrhea. The condition can also produce obstruction and intussusceptions, in addition to bleeding [ 2 , 3 ]. The vast majority of cases occur in the setting of inflammatory bowel disease, particularly in patients with ulcerative colitis.…”

Section: Introductionmentioning

confidence: 99%

Diffuse filiform polyposis of the small intestine without inflammatory bowel disease

et al. 2014

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Filiform polyposis is a rare disease, which typically occurs in patients with inflammatory bowel disease. We report a case of filiform polyposis occurring in a 56-year-old man with no history or evidence of inflammatory bowel disease. The patient’s main symptoms were melena and anemia. We performed an emergency exploratory laparotomy, in which we observed worm-like polyps spread almost along the entire small intestine, and a partial resection of the small intestine to treat bleeding in the bowel was carried out. Two days later, the patient was noted to have melena again, and we performed an abdominal angiographic embolization, successfully stopping the bleeding. Histologic evaluation of the excised specimen revealed chronic inflammatory cells within the lamina propria without hyperplastic or adenomatous epithelial changes. Although the surgery was very successful, careful management of the patient was required, owing to the great risk of re-bleeding.

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Tumor-Like Growth of Giant Inflammatory Polyposis in a Patient with Ulcerative Colitis

Cited by 16 publications

References 14 publications

Filiform Polyposis in Ulcerative Colitis: A Rare Pediatric Case

Filiform Polyposis in Ulcerative Colitis: A Rare Pediatric Case

Extensive Giant Inflammatory Pseudopolyposis in Ulcerative Colitis

Diffuse filiform polyposis of the small intestine without inflammatory bowel disease

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