Tumor-Infiltrating Lymphocyte and Other Cell Therapies for Metastatic Melanoma
Christy Los,
Sebastian Klobuch,
John B. A. G. Haanen
Abstract:Major progress in prolonging survival of patients with advanced melanoma has been made in the past decade because of the development and approval of immune checkpoint inhibitor and targeted therapies. However, for nonresponding or relapsing patients, their prognosis is still dismal. Based on clinical trial data, treatment with adoptive cell therapies holds great promise. In patients with metastatic melanoma progressing on or nonresponsive to single-agent anti–programmed cell death 1, infusion of tumor-infiltra… Show more
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