Tumor-draining lymph nodes: opportunities, challenges, and future directions in colorectal cancer immunotherapy
Yao Wang,
Tingting Zhu,
Qi Shi
et al.
Abstract:Tumor-draining lymph nodes (TDLNs) are potential immunotherapy targets that could expand the population of patients with colorectal cancer (CRC) who may benefit from immunotherapy. Currently, pathological detection of tumor cell infiltration limits the acquisition of immune information related to the resected lymph nodes. Understanding the immune function and metastatic risk of specific stages of lymph nodes can facilitate better discussions on the removal or preservation of lymph nodes, as well as the timing … Show more
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