Tumor de células gigantes costal ocupando todo o hemitórax

Cordeiro, Samuel Zuínglio de Biasi; Cordeiro, Paulo; Sousa, Aureliano Mota Cavalcanti; Lannes, Deborah Cordeiro; Pierro, Gustavo Soares de Moura

doi:10.1590/s1806-37132008000300010

Cited by 18 publications

(11 citation statements)

References 11 publications

(6 reference statements)

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“…This delayed presentation probably contributed to the extremely large tumor size found at the time of surgical resection. While multiple cases of GCT originating from the rib have been reported, the two-dimensional span of 28.0 × 24.0 cm resected in our patient appears to be the largest to date (Table 1) [4, 8–14]. …”

Section: Discussionmentioning

confidence: 87%

Giant Cell Tumor of Rib Arising Anteriorly as a Large Inframammary Mass: A Case Report and Review of the Literature

Sharma

Armstrong

2012

Case Reports in Medicine

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Introduction. Giant cell tumor of the bone is a rare benign lesion that infrequently affects the ribs, and if present, is usually located posteriorly. The rarity of this tumor poses diagnostic and therapeutic problems for physicians, especially when it is located in the anterior arc of the rib in close proximity to the breasts in female patients. Case Presentation. We report the case of a 32-year-old Asian female with a giant cell tumor of her anterior rib, presenting as a large inframammary mass. Computed tomography showed a tumor arising from the 7th rib anteriorly with marginal sclerosis, cortical destruction, and a soft tissue mass. She was treated with surgical resection, and the defect was reconstructed primarily. The surgical specimen measured 28.0 × 24.0 cm. The microscopic examination showed a large number of multinucleate giant cells scattered over the parenchyma. Patient recovered uneventfully and continues to be recurrence-free six years after surgical resection. Conclusion. We report the largest known case of giant cell tumor arising from the anterior aspect of a rib. We recommend including giant cell tumor in the differential diagnosis of chest wall masses especially in female patients, regardless of the size on clinical examination.

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Section: Discussionmentioning

confidence: 87%

Giant Cell Tumor of Rib Arising Anteriorly as a Large Inframammary Mass: A Case Report and Review of the Literature

Sharma

Armstrong

2012

Case Reports in Medicine

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“…GCT consists of proliferation of multinucleated giant cells in the stroma of spindle-shaped mononuclear cells, which are derivatives of monocytes. 3 The multinucleated cells resemble osteoclasts, but are larger and can contain more than 100 nuclei (average 10 to 50). The ratio of cells that form within the same focus may vary.…”

Section: Discussionmentioning

confidence: 99%

Surgical management of rare benign tumors of the sternum

Gritsiuta

Bracken

Downs

et al. 2021

MOJCR

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Primary benign tumors of the sternum are an exceedingly rare entity. Surgical techniques regarding intervention for these lesions are not clearly defined in the literature given their scarcity. Operative techniques include en-bloc resection of the tumor, and this has proven to be successful in preventing local recurrence despite benign nature of the lesion. Given the often extensive defect created by the excision, reconstruction is frequently necessary; depending on the size of the defect, either autologous bone grafting or the use of synthetic materials may be indicated. This study serves to present two cases of rare primary benign tumors of the sternum, giant cell tumors and osteoma spongiosum and to summarize the available literature. We present a review of the literature of 17sternal giant cell tumor cases reported so far including our patient and unique case of osteoma spongiosum of the sternum, that discusses their surgical management, as well as reconstructive techniques that provided an excellent clinical result and a lack of recurrence on long term follow-up.

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“…As the lesion grows, it can encompass the entire circumference of the bone, causing rupture of the cortical bone, but a periosteal reaction is rarely seen. [1256]…”

Section: Discussionmentioning

confidence: 99%

Aggressive giant cell tumor of the anterior arc of the rib

Manjunatha

Ramaswamy

Kumar

2012

J Cytol

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Giant cell tumor of bone also known as osteoclastoma is a distinct clinical, roentgenographic and pathologic entity with specific characteristics. It is a benign but locally aggressive neoplasm, classically seen as a purely lytic lesion of the epiphyseal or metaphyseal-epiphyseal region of long tubular bones extending to the articular surface. It usually occurs after skeletal maturation and is one of the rare bone tumors that more frequently affects women. Even though rarely it can occur in ribs, it usually occurs in the posterior aspect. We report here a case of giant cell tumor originating from the anterior arc of the rib diagnosed on fine needle aspiration cytology.

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Tumor de células gigantes costal ocupando todo o hemitórax

Cited by 18 publications

References 11 publications

Giant Cell Tumor of Rib Arising Anteriorly as a Large Inframammary Mass: A Case Report and Review of the Literature

Giant Cell Tumor of Rib Arising Anteriorly as a Large Inframammary Mass: A Case Report and Review of the Literature

Surgical management of rare benign tumors of the sternum

Aggressive giant cell tumor of the anterior arc of the rib

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