Tumor Budding in Oral Cavity Cancer

Abstract

This work is licensed under Creative Commons Attribution 4.0 License AJBSR.MS.ID.001160.

Prognostic role of tumor budding in oral squamous cell carcinoma: a retrospective study

“…As a result, they determined that TB in the TSCC was a biological marker that predicted a poor prognosis. 18 The findings of our study (P = 0.59, not significant) (Table 3), demonstrated that there is no relationship between the presence or absence of TB and patient survival rates, which is in accordance with previous studies by Joshi et al (2020) 16 and Fernando Candanedo-Gonzalez et al (2020). 18 Nandita et al (2016), 24 investigated the contribution of TB to the diagnosis of OSCC.…”

“…18 The findings of our study (P = 0.59, not significant) (Table 3), demonstrated that there is no relationship between the presence or absence of TB and patient survival rates, which is in accordance with previous studies by Joshi et al (2020) 16 and Fernando Candanedo-Gonzalez et al (2020). 18 Nandita et al (2016), 24 investigated the contribution of TB to the diagnosis of OSCC. For this investigation, 30 histological samples of OSCC with a biopsy-proven diagnosis were chosen.…”

“…Some of these studies have shown that TB is an important prognosticator of LNM, distant metastatic disease and local recurrence. [15][16][17][18] Strong evidence linking TB and LNM has been established, and multivariate analysis shows that TB is associated with aggressive tumor activity and a bad prognosis in instances, suggesting that TB count can be used to gauge the risk of LNM. 1,19 TB count does not require the use of any other expensive techniques or equipment because it is a simple procedure used on a daily basis with the help of H&E stained sections.…”

“…There found no evidence of a significant relationship between TB and the survival rate. 16 Candanedo-Gonzalez et al (2020), 18 investigated incidences of OSCC in the tongue (TSCC), which had a susceptibility to early local spread and recurrence. They reported that TSCC at an early stage (T1/T2N0M0) is not necessarily associated with a favorable prognosis.…”