Tumor-associated macrophages in the prospect of development of targeted anticancer

Ecological photodynamic therapy: New trend to disrupt the intricate networks within tumor ecosystem

“…Certain photodynamic regimens have been developed in order to eliminate the macrophagic population. PDT is one of the therapies that have been directed to reduction of TAMs in the tumor ecosystem by direct destruction [130]. In this context, some PSs have been coupled to ligands of scavenger-receptor expressed on that species [131][132][133], in order to direct therapy to it.…”