Tumid Lupus Erythematosus and Systemic Lupus Erythematosus: A Report on Their Rare Coexistence

Jatwani, Karan; Chugh, Karan; Osholowu, Oluwasegun; Jatwani, Shraddha

doi:10.7759/cureus.7545

Cited by 5 publications

(10 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It runs an intermittent clinical course of relapse and spontaneous resolution without scarring or dyspigmentation. Association with SLE is rare 71,72 …”

Section: Introductionmentioning

confidence: 99%

Cutaneous manifestations of lupus erythematosus: a practical clinicopathological review for pathologists

2021

View full text Add to dashboard Cite

Accurate diagnosis of connective tissue diseases is often challenging, and relies upon careful correlation between clinical and histopathological features, direct immunofluorescence studies and laboratory work‐up. Lupus erythematosus (LE) is a prototype of connective tissue disease with a variety of cutaneous and systemic manifestations. Microscopically, cutaneous LE is classically characterised by an interface dermatitis although other histopathological patterns also exist, depending upon the clinical presentation, location and chronicity of the skin lesions. In this article, we review the clinical, serological, histopathological and direct immunofluorescence findings in LE‐specific and LE non‐specific skin lesions, with an emphasis upon lesser‐known variants, newly described features and helpful ancillary studies. This review will guide general pathologists and dermatopathologists in accurately diagnosing and subclassifying cutaneous LE.

show abstract

“…It runs an intermittent clinical course of relapse and spontaneous resolution without scarring or dyspigmentation. Association with SLE is rare 71,72 …”

Section: Introductionmentioning

confidence: 99%

Cutaneous manifestations of lupus erythematosus: a practical clinicopathological review for pathologists

2021

View full text Add to dashboard Cite

show abstract

“…Have a better prognosis compared to other forms of cutaneous LE. 33 Responds well to topical corticosteroids and antimalarials. 33 Hypertrophic LE Rare variants of LE, which involves extensors of the upper limb and upper trunk.…”

Section: Hair Involvement In Lementioning

confidence: 99%

“…33 Responds well to topical corticosteroids and antimalarials. 33 Hypertrophic LE Rare variants of LE, which involves extensors of the upper limb and upper trunk. 12 Clinically, it presents as verrucous indurated plaques, which sometimes can be mistaken as squamous cell carcinoma.…”

Section: Hair Involvement In Lementioning

confidence: 99%

Skin Changes in Lupus Erythematosus: A Concise Review Lupus Erythematosus and Skin-demystifying the Features

Gupta,

Kumaran

2024

Indian Journal of Rheumatology

View full text Add to dashboard Cite

Lupus erythematosus is an autoimmune disease characterised by the formation of various autoantibodies, leading to the involvement of numerous organ systems like the nervous system, renal system, and cutaneous involvement. Cutaneous involvement is the second most common manifestation after musculoskeletal involvement and can range from minor involvement to severe disabling sequelae. The type of skin manifestation can sometimes predict the underlying systemic involvement, as most patients of acute lupus erythematosus have concomitant systemic involvement in contrast to limited chronic cutaneous LE, which has a low incidence of systemic involvement. The cutaneous manifestations have been included in the Systemic Lupus International Collaborating Clinics (SLICC) and American College of Rheumatology criteria for ease in diagnosing lupus erythematosus patients. Herein, we present a review of various cutaneous manifestations seen in association with systemic lupus erythematosus (SLE) patients and their specific management, which can ease the early diagnosis of the patients and triage the patients that will need close follow-up for systemic involvement.

show abstract

“…Multiple drugs have been described to induce TLE such as tumor necrosis factor-alpha (TNF-a) inhibitors, angiotensin-converting-2 enzyme inhibitors, and bortezomib [26][27][28][29]. TLE has rarely been reported in association with DLE and SLE [30,31]. Indeed, TLE appears to be the least form of CCLE to be seen concomitantly with SLE.…”

Section: Etiopathogenesismentioning

confidence: 99%

Tumid Lupus Erythematosus (TLE): A Review of a Rare Variant of Chronic Cutaneous Lupus Erythematosus (cCLE) with Emphasis on Differential Diagnosis

Daruish,

Ambrogio,

Foti

et al. 2024

Diagnostics

View full text Add to dashboard Cite

Tumid lupus erythematosus (TLE) has been the subject of heated debate regarding its correct nosographic classification. The definition of TLE has changed over time, varying according to the different studies performed. In this review, we address the initial definition of TLE, the changes that have taken place in the understanding of TLE, and its placement within the classification of cutaneous lupus erythematosus (CLE), with a focus on clinical, histopathological, immunophenotypical, and differential diagnosis aspects.

show abstract

Tumid Lupus Erythematosus and Systemic Lupus Erythematosus: A Report on Their Rare Coexistence

Cited by 5 publications

References 9 publications

Cutaneous manifestations of lupus erythematosus: a practical clinicopathological review for pathologists

Cutaneous manifestations of lupus erythematosus: a practical clinicopathological review for pathologists

Skin Changes in Lupus Erythematosus: A Concise Review Lupus Erythematosus and Skin-demystifying the Features

Tumid Lupus Erythematosus (TLE): A Review of a Rare Variant of Chronic Cutaneous Lupus Erythematosus (cCLE) with Emphasis on Differential Diagnosis

Contact Info

Product

Resources

About