Tumeur Triton maligne : à propos d’un cas

Brunet, Anaïs; Hermeziu, Oana; Luciani, Alain; Ortonne, Nicolas

doi:10.1016/j.annpat.2021.02.002

Cited by 2 publications

(3 citation statements)

References 23 publications

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“…A range of cases presentation in the literature we reviewed describe the imaging manifestations (including CT and MRI) correlated with MTT: giant lump, heterogeneity, irregular margins, intratumoral hemorrhage, necrosis, lobulation, calcifications, heterogenous enhancement on postcontrast CT or MRI, hypointense/isointense T1WI and hyperintense T2WI signal on MRI, and diffusion restriction on DWI and ADC 1,8–32,39,40 . Zain et al 20 and Li et al 29 had reported similar conclusions, Li et al pointed out some characteristics common to MTTs and MPNSTs, including ill‐defined margin, intratumoral lobulation, peripheral edema, calcifications, and destruction of adjacent bone tissues.…”

Section: Discussionmentioning

confidence: 71%

“…We compiled data on reported cases of MTT in the recent 6 years (2018–2023, Table 1). 1,6–38 There were totally 37 cases with a mean age of 39.4 years (range 8 months old–75 years old), including 24 male and 13 female patients. Eleven cases originated in the abdomen (30%), 10 cases in the head and neck (27%), 8 cases in the thoracic cavity (21%), 6 cases in the limbs (16%), 1 case in the spine (3%), and 1 case in the buttocks (3%).…”

Section: Results Of Literature Reviewmentioning

confidence: 99%

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Malignant triton tumor of uterus: A case report and literature review

Jiang,

Liu,

et al. 2023

J of Clinical Ultrasound

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Malignant triton tumor (MTT) is a highly aggressive malignant neoplasm, classified as a variant of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation. There are few reports that MTT occurred in urogenital system. In the present study, we report the first MTT occurring in the uterus. A 57‐year‐old woman came to the emergency department due to persistent vaginal bleeding for 2 months. The gynecological palpation found that a club‐shaped excrescence existed in the vagina about 7 cm × 3 cm × 3 cm. The mass located in the lower segment of the uterus and the cervix was confirmed by gynecological vaginal ultrasound and magnetic resonance imaging, which was preliminarily diagnosed as cervical carcinoma. After neoplasm punch biopsy, the pathological diagnosis was malignant triton tumor. The patient finally lost follow‐up. This is the first report about MTT in the uterus and suggests that pathological biopsy combined with imaging examination is necessary for the diagnosis of rarely MTT.

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Section: Discussionmentioning

confidence: 71%

Section: Results Of Literature Reviewmentioning

confidence: 99%

Malignant triton tumor of uterus: A case report and literature review

Jiang,

Liu,

et al. 2023

J of Clinical Ultrasound

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“…Masson described it in 1932 (1). MPNST originates from Schwann cells and neural crest, whereas the MTT differs by a focal rhabdomyoblastic differentiation (2). It received its name "Triton" from the experimentation of Locatelli (3) who succeed in growing a supernumerary limb on Triton salamander's backs after a peripheral nerve graft.…”

Section: Introductionmentioning

confidence: 99%

Malignant Triton tumor of the retroperitoneum: a case report about a rare diagnostic trap and a geriatric challenge

SAUVINET,

ALGHAMDI,

WEINGERTNER

et al. 2024

Preprint

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Background: Malignant Triton Tumor (MTT) constitutes a subtype of Malignant Peripheral Nerve Sheath Tumor, whose retroperitoneal localization is extremely rare: at this time, only some twenty cases reports have been reported since its first description. We present the case of a MTT diagnosed on the histological examination after the mass resection, which was previously considered as myxofibrosarcoma according to biopsy findings. Case presentation: A 76-year-old woman suffered from femoral pains resulting from a left retroperitoneal mass, 33cm in diameter, arising from the major psoas muscle. In view of the so-called diagnosis and the age, we decided to perform an up-front R1 left compartmentectomy sparing pancreas without neoadjuvant treatment. The tumor was found to involve the femoral trunk nerve, necessitating its resection so that the piece remains unfragmented. Immunohistochemical analysis finally revealed a MTT with a focal positivity for S100, as well as a focal staining with markers of skeletal muscle differentiation. The postoperative course was uneventful besides the foreseeable femoral paralysis, and adjuvant irradiation was proposed. Tumor heterogeneity can explain the discrepancy between the settings of the core needle biopsy and the definitive histological conclusions, and highlights the difficulty bringing the correct diagnosis with a biopsy alone. Nevertheless, according to the acknowledged poor prognosis, the risk-benefit balance in this particular context should have discouraged a wider resection even if MTT was diagnosed before surgery. Conclusions: This case report raises the question of the major place of geriatric preoperative assessment and the appropriateness of multi-organs removals in elder patients, more specifically in those presenting aggressive sarcomas such as MTT.

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Tumeur Triton maligne : à propos d’un cas

Cited by 2 publications

References 23 publications

Malignant triton tumor of uterus: A case report and literature review

Malignant triton tumor of uterus: A case report and literature review

Malignant Triton tumor of the retroperitoneum: a case report about a rare diagnostic trap and a geriatric challenge

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