Tumeur testiculaire bilatérale à cellules de Leydig : à propos d’un cas

Slama, A.; Elleuch, Ahmed; Yacoubi, M. T.; Sorba, N. Ben; Mosbah, A.

doi:10.1016/s0003-4401(03)00045-7

Cited by 6 publications

(1 citation statement)

References 9 publications

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“…The vast majority of LCTs in children are benign, contrasting with the 5% to 10% malignancy see in LCTs of adults [70,78]. Rare cases of malignancy have been described in bilateral cases in children [79]. Criteria for malignancy have not been well established for children or adults.…”

Section: Leydig Cell Tumorsmentioning

confidence: 99%

Perspectives in Pediatric Pathology, Chapter 25. Testicular and Paratesticular Tumors in the Pediatric Age Group

et al. 2016

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Testicular tumors in the prepubertal age are relatively rare, representing only 9.4% of the total testicular and paratesticular specimens from a 20-year review performed at a large pediatric hospital [ 1 ]. They account for 1% to 2% of all solid tumors in the pediatric age group, with an annual incidence between 0.5/100 000 and 2/100 000 boys according to Coppes et al [ 2 ] and data from the Prepubertal Testicular Tumor Registry [ 3 ]. Similar to other neoplasms afflicting children, a bimodal age distribution is observed. The first peak is between birth and 3 years of age, and a second one occurs at the onset of puberty, extending to the fourth decade. Reports on their frequency vary because some investigators include the adolescent period, while others do not [ 4 ]. The vast majority of testicular tumors are germ cell neoplasms, accounting for 95% across all ages [ 5 ]. In children, germ cell tumors also predominate, representing 71% of all testicular neoplasms. These include yolk sac tumors (49%), teratomas (13%), seminomas and mixed germ cell tumors (9%), and sex-cord stromal tumors (29%). Malignant potential is significantly lower (less than 70%) in the pediatric age group compared to adults (90%) [ 6 ]. According to Pohl et al, 74% of prepubertal testicular tumors are benign [ 7 ].

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Section: Leydig Cell Tumorsmentioning

confidence: 99%

Perspectives in Pediatric Pathology, Chapter 25. Testicular and Paratesticular Tumors in the Pediatric Age Group

et al. 2016

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Macroorchidisms Secondary to Functioning Tumors during Childhood

Nistal¹,

González‐Peramato

Serrano

2017

Clues in the Diagnosis of Non-Tumoral Testicular Pathology

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Enucleation for Prepubertal Leydig Cell Tumor

et al. 2006

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Prepubertal boys with isosexual precocious pseudopuberty, an isolated testis mass, increased testosterone and low or normal gonadotropin levels can reliably be diagnosed with Leydig cell tumors. Based on the ability to establish the diagnosis preoperatively and the universal benign behavior of unilateral, prepubertal Leydig cell tumor, we believe these patients are best treated with testis sparing enucleation of the tumor. In view of the high likelihood that this tumor in prepubertal boys is benign, a transscrotal surgical approach should be considered.

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Tumeur testiculaire bilatérale à cellules de Leydig : à propos d’un cas

Cited by 6 publications

References 9 publications

Perspectives in Pediatric Pathology, Chapter 25. Testicular and Paratesticular Tumors in the Pediatric Age Group

Perspectives in Pediatric Pathology, Chapter 25. Testicular and Paratesticular Tumors in the Pediatric Age Group

Macroorchidisms Secondary to Functioning Tumors during Childhood

Enucleation for Prepubertal Leydig Cell Tumor

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