Tumeur juvénile de la granulosa de l’ovaire: à propos d’un cas

Abstract

Ovarian sex cord tumors are rare tumors that develop at the expense of non-germ cell ovarian. The pathogenesis of these tumors remains undetermined and several cellular and molecular alterations may be involved in the development of juvenile granulosa cell tumors. For two decades, the individualization of juvenile granulosa cell tumors has been a major advance in the treatment of these children's tumors. However, their natural history is reported in the literature and through a short series and reliable prognostic factors are to establish. We report the case of a girl of 8 years who presented with abdominal-pelvic mass gradually increasing size, to surgical exploration found a huge abdominal mass at the expense of the left ovary. Histology and objective immunolabeling a tumor of the juvenile form of granulosa.

Adult granulosa tumor of the ovary about a case

“…The information provided by MRI does not appear to be superior to that of pelvic ultrasound performed under excellent technical conditions by an experienced sonographer. 9 Our patient's ultrasound confirmed the adnexal origin of a nodulocystic mass.…”

Premature Puberty Revealing an Ovarian Tumor in a Five-Year-Old Girl

“…This could be explained by a circadian variation of estradiol secretion by the tumor cells. Moreover, a low specificity of plasma estradiol determination by conventional methods is sometimes evoked and could also contribute to this clinico-biological discordance [5].…”