Tumefactive demyelination associated with systemic lupus erythematosus

Abstract

Systemic lupus erythematosus (SLE) is a chronic inflammatory multi-system disease characterised by varied clinical manifestation and immunological abnormalities. The clinical presentation of the disorder has wide spectra, from an asymptomatic presentation to a severe life-threatening disease affecting several organs. The sole manifestation of lupus erythematosus could be neurological syndrome, where diagnosis of SLE is difficult to establish. The authors intended to report a young female, who initially developed left-sided hemiparesis due to tumefactive demyelination, later on diagnosed as case of SLE. The association of tumefactive demyelination and SLE has not been previously reported in the literature.

A case of recurrent tumefactive demyelination or tumefactive multiple sclerosis

“…HIV), autoimmune disorders (e.g. Sjogren syndrome, systemic lupus erythematosus (SLE), Behcet disease and neuromyelitis optica) and drugs (tacrolimus) [8][9][10][11][12][13][14][15][16] .…”