Tularaemia outbreak in Castilla y León, Spain, 2007: an update

Allué, Miguel; Sopeña, C Ruiz; Gallardo, M T; Mateos, L; Vián, E; Garcia, Melissa; Ramos, Jordão Raphael Fujii; Berjón, A C; Viña, M C; Garcia, M. P. Romero; Yanez, J Pena; González, Leonila; Munoz, T; Andrés, Cristina; Tamames, Sonia; Ruiz, C; Iglesias, Liliana; Castrodeza, J.

doi:10.2807/ese.13.32.18948-en

Cited by 32 publications

(11 citation statements)

References 2 publications

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“…The most common clinical form was typhoidal (71.6%, which is usually characterized by a severe disease with high fever and confusion, occurring through different modes of infection), followed by ulceroglandular (14.6%, characterized by skin ulcers with regional lymphadenopathy), glandular (12.6%, with only regional lymphadenopathy), and oculoglandular (1.2%, related to conjunctivitis and preauricular lymphadenopathy). In this context, Allue et al [ 17 ] stated that harvesting tasks trigger aerosols being able to carry F. tularensis . Another hypothesis by this same group referred to environmental conditions (mild winters and dry springs) that could have contributed to tularemia outbreaks along with a reservoir and infection source diversity [ 17 ].…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…In this context, Allue et al [17] stated that harvesting tasks trigger aerosols being able to carry F. tularensis. Another hypothesis by this same group referred to environmental conditions (mild winters and dry springs) that could have contributed to tularemia outbreaks along with a reservoir and infection source diversity [17]. A total of 153 cases (6.12 per 100,000 inhabitants) were informed in 2008, with Palencia having the highest number of cases (24.36 per 100,000 inhabitants), followed by Zamora (13.18 per 100,000 inhabitants) and Soria (6.41 per 100,000 inhabitants) (Table 2).…”

Section: Outbreaks In Humansmentioning

confidence: 99%

“…The most common clinical form was ulceroglandular tularemia, followed by glandular and typhoid forms. A second human outbreak also took place in the same region between 2007 and 2008, after 10 years of no epidemiological activity, linked to common vole overcrowding, and the most prevalent clinical forms in this case were typhoidal and pneumonic tularemia [ 4 , 17 , 18 ]. The infection source was through inhalation.…”

Section: Introductionmentioning

confidence: 99%

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Tularemia Outbreaks in Spain from 2007 to 2020 in Humans and Domestic and Wild Animals

et al. 2021

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In this study, tularemia outbreaks associated with humans and several domestic and wild animals (Iberian hares, wild rabbits, voles, mice, grey shrews, sheep, dogs, foxes, wolves, ticks, and river crayfish) are reported in Spain from 2007 to 2020. Special attention was paid to the outbreaks in humans in 2007–2009 and 2014–2015, when the most important waves occurred. Moreover, positive rates of tularemia in lagomorphs were detected in 2007–2010, followed by negative results in 2011–2013, before again returning to positive rates in 2014 and in 2017 and in 2019–2020. Lagomorphs role in spreading Francisella tularensis in the epidemiological chain could not be discarded. F. tularensis is described for the first time infecting the shrew Crocidura russula worldwide, and it is also reported for the first time infecting wild rabbits (Oryctolagus cuniculus) in Spain. Serological positives higher than 0.4% were seen for sheep only from 2007–2009 and again in 2019, while serological rates greater than 1% were revealed in dogs in 2007–2008 and in wild canids in 2016. F. tularensis were detected in ticks in 2009, 2014–2015, 2017, and 2019. Lastly, negative results were achieved for river crayfish and also in environmental water samples from 2007 to 2020.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Outbreaks In Humansmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Tularemia Outbreaks in Spain from 2007 to 2020 in Humans and Domestic and Wild Animals

et al. 2021

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“…1 weitere ausschließlich / überwiegend tierpathogene Spezies mit fraglicher humanpathogener Relevanz werden nicht aufgelistet2 bezogen auf humane Infektionen durch Francisella spp 3. gelegentlich auch als Subspezies von F. tularensis betrachtet (F. tularensis spp.…”

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Die Tularämie in Deutschland

Kohlmann¹,

Geis²,

Gatermann³

2014

Dtsch med Wochenschr

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The bacterium Francisella tularensis is known for more than 100 years by now as the etiological agent of the disease tularemia, a zoonotic infection with a worldwide distribution in the Northern Hemisphere. The prevalence of tularemia shows a wide geographic variation, being comparably infrequent in Germany. Tularemia can present itself with multiple clinical manifestations including ulceroglandular, glandular, oropharyngeal, oculoglandular, respiratory and typhoidal forms. Due to the low prevalence and the unspecific symptomatology, a rapid diagnosis and early start of an effective therapy are rarely obtained. Thus, in this article we summarize important aspects concerning etiology, ecology and routes of transmission, recent epidemiologic situation, clinical picture, diagnostics and treatment of tularemia, focusing on the situation in Germany.

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Tularaemia: A challenging zoonosis

Carvalho

Zé-Zé

et al. 2014

Comparative Immunology, Microbiology and Infectious Diseases

109

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a b s t r a c tIn recent years, several emerging zoonotic vector-borne infections with potential impact on human health have been identified in Europe, including tularaemia, caused by Francisella tularensis. This remarkable pathogen, one of the most virulent microorganisms currently known, has been detected in increasingly new settings and in a wide range of wild species, including lagomorphs, rodents, carnivores, fish and invertebrate arthropods. Also, a renewed concern has arisen with regard to F. tularensis: its potential use by bioterrorists. Based on the information published concerning the latest outbreaks, the aim of this paper is to review the main features of the agent, its biology, immunology and epidemiology. Moreover, special focus will be given to zoonotic aspects of the disease, as tularaemia outbreaks in human populations have been frequently associated with disease in animals.

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Tularaemia outbreak in Castilla y León, Spain, 2007: an update

Abstract: Binary file ES_Abstracts_Final_ECDC.txt matches

Cited by 32 publications

References 2 publications

Tularemia Outbreaks in Spain from 2007 to 2020 in Humans and Domestic and Wild Animals

Tularemia Outbreaks in Spain from 2007 to 2020 in Humans and Domestic and Wild Animals

Die Tularämie in Deutschland

Tularaemia: A challenging zoonosis

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