Tucumã (<i>Astrocaryum aculeatum</i>) Prevents Oxidative and DNA Damage to Retinal Pigment Epithelium Cells

Bonadiman, Beatriz da Silva Rosa; Chaves, Cláudia Maria Osório; Assmann, Charles Elias; Weis, Grazielle Castagna Cezimbra; Alves, Audrei de Oliveira; Gindri, Amanda Leitão; Chaves, Cláudio; Cruz, Ivana Beatrice Mânica da; Zamoner, Ariane; Bagatini, Margarete Dulce

doi:10.1089/jmf.2020.0171

Cited by 5 publications

(4 citation statements)

References 25 publications

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“…The potential of the tucumã extract in the prevention of molecular damage to retinal epithelium cells (RPE) was evaluated by Bonadiman et al [ 69 ]. In vitro protocols were performed to verify the cytoprotective effect with different concentrations of tucumã extract (5, 10, 50, 100, and 500 μg/ml) in RPE cells exposed to the oxidizing agent hydrated paraquat dichloride at a 30 μM for 6 h. The concentrations of 5, 10, and 50 μg/ml of tucumã extract did not cause apoptosis and necrosis in ARPE-19 cells.…”

Section: Biological Effects Of Fruits Of Amazonian Palm Treesmentioning

confidence: 99%

Amazonian palm tree fruits: From nutritional value to diversity of new food products

Amorim,

Godoy

et al. 2024

Heliyon

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Section: Biological Effects Of Fruits Of Amazonian Palm Treesmentioning

confidence: 99%

Amazonian palm tree fruits: From nutritional value to diversity of new food products

Amorim,

Godoy

et al. 2024

Heliyon

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“…Liquid nitrogen was used for tempering. The fully melted sample was pipetted into the bottom of an NMR tube, filling its bottom to 1 cm (~0.57 ± 0.05 mL), stored at different temperatures (5,10,15,18,20,25,30 and 40 ± 1 °C), and then measured. Bruker's Minispec V2.58 Rev12 and Minispec plus V1.1 Rev05 software were used to collect the SFC data.…”

Section: Solid Fat Content (Sfc)mentioning

confidence: 99%

“…These compounds reportedly impart significant beneficial bioactivity. The bioactive components found in AVP have been demonstrated to impart antimicrobial, antifungal [16], anti-inflammatory [14], antiproliferative [17], cytoprotective [18], skin-protective [8] and antioxidant activity [15,19,20]. Non-lipid bioactive compounds have not been reported in AVK lipid extractions.…”

Section: Introductionmentioning

confidence: 99%

Extending the Physical Functionality of Bioactive Blends of Astrocaryum Pulp and Kernel Oils from Guyana

Bouzidi,

Deonarine,

Soodoo

et al. 2024

Cosmetics

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Natural lipids with nutritional or therapeutic benefits that also provide desired texture, melting and organoleptic appeal (mouthfeel, skin feel) are difficult to procure for the food and cosmetics industries. Natural Astrocaryum pulp oil (AVP) and kernel fat (AVK) from Guyana were blended without further modification to study the potential of extending the physical functionality of the blends beyond that of crude AVK and AVP. An evaluation of non-lipid components by ESI-MS indicated twenty-four (24) bioactive molecules, mainly carotenoids (90%), polyphenols (9%) and sterols (1%) in AVP, indicating important health and therapeutic benefits. Only trace-to-negligible amounts of these compounds were detected in AVK. The thermal transition phase behavior, solid fat content (SFC), microstructure and textural properties of five AVP/AVL blends were used to construct phase diagrams of the AVK/AVP binary system. Binary phase diagrams constructed from the cooling and heating DSC thermograms of the mixtures and description of the liquidus line indicated a mixing behavior close to ideal with a tendency for order, with no phase separation. Melting onsets, solid fat content and measurements of solid-like texture all predictively increased with increasing AVK content. The descriptive decay parameters obtained for SFC, crystal size, hardness, firmness and spreadability were similar and predictive and indicate the way the binary system structure approaches that of a liquid or a functional solid. The bioactive content of the blends was accurately calculated; the work provides a blueprint for the blending of AVP and AVK to deliver targeted bioactive content, stability, spreadability, texture, melting profile, organoleptic appeal and solid content. SFCs at 20 °C ranged from 9.1% to 39.1%, melting onset from −17.5 °C to 27.8 °C, hardness from 0.1 N to 3.5 N and spreadability from 3.3 N·s to 147.1 N·s; indicating a useful dynamic range of physical properties suitable for bioactive oils to bioactive butters.

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“…The pulp oils and kernel fats [34] of AV and AA contain fat-soluble bioactive compounds including carotenoids [35], phenolic compounds [36] and sterols [35]. In vitro experiments indicate antimicrobial, antifungal [37], anti-inflammatory [35], antiproliferative [38], cytoprotective [39], skin-protective [7] and antioxidant [36,40,41] activity for these lipids.…”

Section: Introductionmentioning

confidence: 99%

Molecular, Crystalline, and Microstructures of Lipids from Astrocaryum Species in Guyana and Their Thermal and Flow Behavior

Deonarine,

Soodoo,

Bouzidi

et al. 2024

Thermo

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The phase behavior of lipids extracted from Astrocaryum vulgare (AV) and Astrocaryum aculeatum (AA) pulp and kernels and their microstructural, thermal and flow properties were studied. The lipid profiles, crystal structures, microstructures, thermal stabilities and flow behaviors of these lipids provided important structure–function information that are useful to assess potential applications in the food, cosmetic and pharmaceutical industries. AV and AA fruits were sourced from the lowlands and rainforests, respectively, of Guyana. AV and AA pulp oils (AVP and AAP) were distinguished from each other in composition and unsaturation, with AVP oils being predominated by a di-unsaturated TAG (2-(palmitoyloxy)propane-1,3-diyl dioleate (POO)) and AAP oils predominated by propane-1,2,3-triyl trioleate (OOO); there were unsaturation levels of 65% and 80%, respectively. The main fatty acids in AVP oils were oleic, palmitic and stearic; for AAP, these were oleic, linoleic, palmitic and stearic. The kernel fats of AV and AA were similar in composition and had saturation levels of 80%, being mainly comprised of tri-saturated TAGs propane-1,2,3-triyl tridodecanoate (LLL) and 3-(tetradecanoyloxy)propane-1,2-diyl didodecanoate (LML). The onset of mass loss (T5%on) of AV and AA pulp oils were similar at 328 ± 6 °C, which were 31 °C ± 9 higher compared to that of the kernel fats, which demonstrated similar T5%on = 293 ± 7 °C. AA and AV pulp oils were liquid at room temperature, with melting points of −5 ± 1 °C and 3 ± 1 °C, respectively; both kernel fats were solid at room temperature, packing in β′ (90% of crystals) and β (10% of crystals) polymorphic forms and melting almost identically at 30 ± 1 °C. Pulp oils demonstrated sporadic nucleation at the onset of crystallization with slow growth into rod-shaped crystallites, leading to an approximately 50% degree of crystallization at undercooling of approximately 40K. Nucleation for kernel fats was instantaneous at undercooling of approximately 23K, demonstrating a spherulitic growth pattern incorporating crystalline lamella and a 90% degree of crystallization. Kernel fats and pulp oils demonstrated Newtonian flow behavior and similar dynamic viscosity in the melt, approximately 28.5 mPa·s at 40 °C. The lipid profiles of AVP and AAP oils were dominated by unsaturated TAGs, suggesting potential nutrition and health benefits, particularly compared to other tropical oils with higher saturation levels, such as palm oil. AAP oil in particular is as unsaturated as olive oil, contains high levels of beta carotene and provides a unique flavor profile. The AAK and AVK lipid profiles and phase transformation indicate potential for applications where a high solid fat content and medium-chain fatty acids are required. Their high lauric and myristic acid content makes them similar to industrially important tropical oils (coconut and palm kernel), suggesting their use in similar formulations. The melting point and plasticity of the kernel fats are similar to that of cocoa and shea butters, suggesting use as replacements in cosmetics, foods and confections. There is, however, the need to better understand their nutritional status and effects on health.

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Tucumã (Astrocaryum aculeatum) Prevents Oxidative and DNA Damage to Retinal Pigment Epithelium Cells

Cited by 5 publications

References 25 publications

Amazonian palm tree fruits: From nutritional value to diversity of new food products

Amazonian palm tree fruits: From nutritional value to diversity of new food products

Extending the Physical Functionality of Bioactive Blends of Astrocaryum Pulp and Kernel Oils from Guyana

Molecular, Crystalline, and Microstructures of Lipids from Astrocaryum Species in Guyana and Their Thermal and Flow Behavior

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