“…23,24,45,50,51 Both nonbiodegradable and biodegradable materials such as silicone elastomer, Millipore™, polyethylene, polytetrafluoroethylene (PTFE), polyvinylidenefluoride (PVDF), poly(acrylonitrile-co-vinyl chloride) (PAN-PVC), collagen, chitosan, PLGA, and polycaprolactone (PCL), and so on, have been fashioned into tubes that act as nerve guidance channels for experimentally repairing transected nerves. 4,6,25,[52][53][54] Particularly, semipermeable hollow fiber channels seeded with fetal spinal cord tissue or Schwann cells have been shown to markedly promote axonal growth across a gap in adult rat spinal cord. 5,25 Anatomical and physiological data have indicated that hollow fiber devices could be as effective as autografts.…”