Tubular apocrine adenoma with perineural invasion

Burket, John M.; Zelickson, Alvin S.

doi:10.1016/s0190-9622(84)70221-0

Cited by 33 publications

(19 citation statements)

References 7 publications

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“…Both tumors have many histological similarities; in fact they have been regarded as identical by some authors [ 19,20]. In our case, however, the luminal cells did not show decapitation secretion, and there was no connection with the overlying epidermis, features considered typical of TAA [21]. Carcinocmbryonic antigen and epithelial membrane antigen arc not suitable for differentiating PEA from TA A, since both react with either eccrine or apocrine glands, although they are useful to specify the glandular nature of the tissue.…”

Section: Discussionsupporting

confidence: 44%

Papillary Eccrine Adenoma

Aloi

Pich²

1991

Dermatology

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A case of papillary eccrine adenoma of the thigh of a 63-year-old woman is reported. Histologically, the tumor was composed of cystic dilated and branching tubular structures with papillary projections into the lumen, surrounded by a fibrous stroma. In addition, in some areas it was composed almost exclusively of solid strands of epithelial cells. The tumoral eccrine differentiation was assessed by immunohistochemical studies. Problems of differential diagnosis with low-grade sweat gland carcinoma and with tubular apocrine adenoma are discussed.

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Section: Discussionsupporting

confidence: 44%

Papillary Eccrine Adenoma

Aloi

Pich²

1991

Dermatology

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“…[6] The finding of a tubular apocrine adenoma in a female of middle age in our case is in concordance with what others have reported. [1][2][3][4][5][6][7]10,12,[14][15][16][17][18] Tubular apocrine adenoma is found most commonly on the scalp but lesions have also been described at a variety of other sites including the face, [6] eyelid, [18] axilla, [3] leg and genitalia. [4,11,17] However, Lee et al reported a case in the external auditory canal.…”

Section: Discussionmentioning

confidence: 99%

“…The relatively limited number of reported cases has posed hindrance to complete understanding of this tumor but this is a rare tumor that the pathologist should be aware of and consider within their differential diagnosis as there is some tendency for perineural invasion. [16] …”

Section: Discussionmentioning

confidence: 99%

Tubular Apocrine Adenoma – A Case Report of Rare Sweat Gland Tumor

Sharma¹,

Kundal²,

Singh³

2017

Ann. Int. Med. Den.Res.

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“…A connection to the epidermis or infundibulum has often been demonstrated in published cases of TA, yet these lesions were variously interpreted as PEA or TAA, not as SCAP. [1][2][3]9,14,[18][19][20][21][22][23][24][25][26][27][28] Connection of the tumors to the infundibulum has been used by some authorities as an argument to support apocrine differentiation. 2,3 One of the observers diagnosed a lesion in this series as SCAP even if it exhibited a single focus in which glandular elements were in continuity to the follicular infundibulum (Fig.…”

Section: Discussionmentioning

confidence: 99%

Tubular Adenoma and Syringocystadenoma Papilliferum: A Reappraisal of Their Relationship. An Interobserver Study of a Series, by a Panel of Dermatopathologists

Kazakov¹,

Bisceglia²,

Calonje³

et al. 2007

The American Journal of Dermatopathology

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Tubular adenoma (TA) and syringocystadenoma papilliferum (SCAP) may show histopathological overlap, with some lesions having features of both neoplasms (SCAP + TA). TA has been recently suggested to represent a carcinoma. Four observers blindly assessed 67 cases of TA, SCAP, and their lookalikes (poroma, apocrine adenoma, apocrine carcinoma; all lesions focally featuring a pseudopapillary pattern), and classified the lesions into one of four categories: (1) TA, (2) SCAP, (3) SCAP + TA, and (4) others. Lesions were also classified as benign or malignant. In only 29 cases was there unanimous agreement among the four observers, who classified 22 lesions as TA, three as SCAP, and four cases as others. Of the 38 cases where there was interobserver diagnostic variation, in 30, the diagnosis varied between TA or SCAP or SCAP + TA; the remainder fell in the others category. Analysis of the factors leading to interobserver variability indicated that diagnostic problems occurred when there were any of the following: epidermal acanthosis, papillomatosis, connection of the neoplastic tubules to the overlying epidermis and/or follicular infundibula, and plasma cell infiltration. These features accounted for the morphological overlap between TA and SCAP. All observers agreed that the lesions were benign; the only apocrine carcinoma included was recognized as such by all observers. From the study, it was concluded that TA may arise in the deep dermis without any epidermal connection, or, in other cases, it may be more superficially located with or without an epidermal connection. It may be reasonably inferred that, possibly as a response to infection, there may be accompanying plasma cells and variable acanthosis and papillomatosis, such that the appearances are those of "pure" SCAP, or lesions may have features "intermediate" or overlapping between TA and SCAP.

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Tubular apocrine adenoma with perineural invasion

Cited by 33 publications

References 7 publications

Papillary Eccrine Adenoma

Papillary Eccrine Adenoma

Tubular Apocrine Adenoma – A Case Report of Rare Sweat Gland Tumor

Tubular Adenoma and Syringocystadenoma Papilliferum: A Reappraisal of Their Relationship. An Interobserver Study of a Series, by a Panel of Dermatopathologists

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