Tuberculous dacryoadenitis in a Scottish teenager

Schmoll, Conrad; MacRae, Maisie; Mulvihill, Alan; Murray, Ronan J.; Cunningham, Steve; McKenzie, Karen

doi:10.1136/bjo.2008.139428

Cited by 11 publications

(5 citation statements)

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“…Both cases were diagnosed with biopsy and responded well to treatment with anti-TB therapy. In all but the single case from the UK,9 the TB dacryoadenitis occurred in immigrants from endemic areas 10 11. We found no previously documented cases of dacryoadenitis in the USA.…”

Section: Discussionmentioning

confidence: 51%

“…Only one case of dacryoadenitis was described among the 18 cases reported. One case report in the UK described a 14-year-old girl with a left-sided superotemporal orbital mass 9. A biopsy showed necrotising granulomatous inflammation of the lacrimal gland, and the patient had a positive tuberculin skin test.…”

Section: Discussionmentioning

confidence: 99%

“…Presumptive diagnosis usually involves suspicious clinical histopathological findings plus 1 of the following: systemic findings consistent with TB infection, positive interferon gamma release assay or positive tuberculin skin test 14. Diagnosis can be substantiated through response to treatment 9–11…”

Section: Discussionmentioning

confidence: 99%

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Tuberculosis presenting as dacryoadenitis in the USA

2019

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A 25-year-old Filipino woman living in the USA was evaluated for a 5-month history of left eye pain and a subsequent orbital mass. Histopathological analysis of the lacrimal mass showed a mixed inflammatory process with necrotising granulomas and positive cultures for Mycobacterium tuberculosis. She was treated with antituberculosis therapy, with resolution of symptoms. Tuberculosis dacryoadenitis is extremely rare in the USA and other developed countries. It requires a high degree of clinical suspicion with special attention to the patient’s history to make the correct diagnosis. It can be treated successfully with antituberculosis therapy.

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Section: Discussionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 99%

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Tuberculosis presenting as dacryoadenitis in the USA

2019

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“…Orbital tuberculosis usually presents in five forms: classical periostitis, orbital soft tissue involvement, and cold abscess with or without bony destruction, orbital tuberculosis spread from the paranasal sinuses and tuberculous dacryoadenitis. Orbital tuberculosis has been reported as enlarging orbital lesions, 1 lacrimal abscess and discharging sinus 2…”

Section: Discussionmentioning

confidence: 99%

Acute lacrimal gland swelling with intracranial extension and without any neurological features – A rare case report

Hina

Monga²,

Khan³

et al. 2018

Saudi Journal of Ophthalmology

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We report a case of young adult female with swelling in the superolateral aspect of left orbit for two weeks which was diagnosed as tubercular dacryoadenitis with intracranial extension without any neurological features. Tubercular dacryoadenitis is very rare but still makes an important differential diagnosis of lacrimal gland swellings especially in endemic areas like India. Few cases of tubercular dacryoadenitis have been reported in the past; but not a single case with intracranial extension in young adults with short history and without neurological symptoms. Although radiological investigations are routinely done in orbital lesions, it is advisable do so even in acute cases to look for intracranial extension before the appearance of neurological features. Tubercular dacryoadenitis though rare, should be kept as a differential diagnosis of acute or chronic lacrimal gland swellings in endemic areas.

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“…Another 14 cases of orbital TB have been described in literature after their report. [2][3][4][5][6][7][8] Orbital TB has been categorised into five clinical groups. 1 Classical periostitis was the most common subtype reported by Madge et al followed by orbital TB with bone involvement and orbital soft tissue tuberculoma / cold abscess with no bony destruction.…”

Section: Discussionmentioning

confidence: 99%