Tuberculous Adenitis with Concurrent Hodgkin Lymphoma: A Case Report

Khan, Fahmi Yousef; Kamel, Antoun; Khalifa, Mahmoud A.; Muthanna, Bassam; Adam, Mohammad

doi:10.5001/omj.2020.62

Cited by 4 publications

(4 citation statements)

References 10 publications

(8 reference statements)

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“…6 Fever, night sweats, and weight loss are symptoms of both TB and HL. 7 In the present case report, we report a difficult rare case of a female patient with HL mimicking TB because of the similarity of clinical and radiological findings. pain, productive cough, and dizziness for 3 days.…”

Section: Introductionmentioning

confidence: 80%

“…However, it could be challenging to distinguish between HL and tuberculosis (TB) due to the overlap of clinical symptoms leading to misdiagnosis 6 . Fever, night sweats, and weight loss are symptoms of both TB and HL 7 . In the present case report, we report a difficult rare case of a female patient with HL mimicking TB because of the similarity of clinical and radiological findings.…”

Section: Introductionmentioning

confidence: 87%

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A difficult case of Hodgkin lymphoma mimicking tuberculosis in a young female patient: A case report

Jamal

Farho

Hariri

et al. 2023

Clinical Case Reports

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Key Clinical Message Due to overlapping clinical symptoms, it may be difficult to distinguish between Hodgkin lymphoma and tuberculosis. Repeated investigations, especially biopsy and histopathological examination, may be helpful to establish a correct diagnosis. Herein, we present a case of Hodgkin's lymphoma misdiagnosed as tuberculosis so we always need evidence‐based medicine in our medical life. Abstract Distinguishing between Hodgkin's Lymphoma and tuberculosis is challenging. A 23‐year‐old patient has been diagnosed with tuberculosis; based on clinical and radiological findings. After the therapy, her condition worsened. Cervical lymphadenopathy was detected. A biopsy was performed and the diagnosis was classical Hodgkin lymphoma. After the treatment, the patient improved significantly.

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Section: Introductionmentioning

confidence: 80%

Section: Introductionmentioning

confidence: 87%

A difficult case of Hodgkin lymphoma mimicking tuberculosis in a young female patient: A case report

Jamal

Farho

Hariri

et al. 2023

Clinical Case Reports

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show abstract

“…Though existence of two different disease processes affecting the superficial and deep nodes separately is not impossible, it is practically rare. However, there have been reports of coexistence of malignancy and TB 6. Biopsy of deep nodes was, therefore, a standby plan in case there was no response to ATT.…”

Section: Discussionmentioning

confidence: 99%

“…The safety of the patient had to be safeguarded as such attempts would have a higher risk-benefit ratio. Two different pathologies causing generalised lymphadenitis at the same time was unlikely though not impossible as TB and malignancy are known to coexist 6. A wait-and-watch policy was, therefore, discussed with the patient with an open option of proceeding with abdominal/mediastinal node biopsy in case of inadequate or no response to antitubercular treatment (ATT).…”

Section: Differential Diagnosismentioning

confidence: 99%

Massive generalised lymphadenopathy: a rare presentation of tuberculosis with a favourable outcome

Sahasrabudhe¹,

Senthamizh²,

Meshram³

2023

BMJ Case Rep

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We present a case of massive generalised necrotic lymphadenopathy due to tuberculosis (TB) without any solid organ involvement. An immunocompetent man in his early 30s presented 1 year ago with weight loss, cough and a solitary cervical node. Contrast-enhanced CT scan thorax showed massive enlargement of almost all groups of mediastinal nodes with large areas of necrosis. Ultrasound examination revealed multiple necrotic abdominal nodes. Core biopsy of the supraclavicular node confirmed TB by histopathology and molecular testing. His Mantoux test was negative suggesting tuberculin anergy. Biopsy of deep nodes was avoided. He responded well to standard antitubercular treatment in weight-corrected doses along with systemic steroids which were prescribed to prevent further breakdown/rupture of nodes. After the extended TB treatment for 12 months, he is asymptomatic and has gained weight, with complete resolution of cervical node and near complete resolution of all deep nodes.

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Hodgkin lymphoma and bone marrow tuberculosis: A coincidence

Cahyanur,

Chairani Siregar,

Stephanie Harahap

et al. 2023

ASJO

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Hodgkin lymphoma is a type of lymphoma that occurs due to mutations in B cells of the lymphatic system. Cases of lymphoma often have identical clinical manifestations with tuberculosis (TB), making the diagnosis difficult. Case of lymphoma coincidence with TB is rare, but can probably cause complexity in the diagnosis and treatment of patients. We report the case of a 20-year-old male patient who presented with symptoms of prolonged fever, enlarged lymph nodes, loss of weight, and weakness. The patient was treated with antituberculosis medication, but the symptoms did not improve. Several investigations were carried out on the patient. Lymph node biopsy showed scattered tumor cells consisting of mononuclear Hodgkin cells with several Reed–Sternberg cells. On the other hand, the bone marrow aspiration examination was positive for Mycobacterium tuberculosis. Reconsideration of confirmed diagnosis and repeated diagnostic process are required when there is a discrepancy in clinical features, radiological findings, or treatment responses.

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Tuberculous Adenitis with Concurrent Hodgkin Lymphoma: A Case Report

Cited by 4 publications

References 10 publications

A difficult case of Hodgkin lymphoma mimicking tuberculosis in a young female patient: A case report

A difficult case of Hodgkin lymphoma mimicking tuberculosis in a young female patient: A case report

Massive generalised lymphadenopathy: a rare presentation of tuberculosis with a favourable outcome

Hodgkin lymphoma and bone marrow tuberculosis: A coincidence

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