Tuberculosis y actinomicosis. Un caso pediátrico de comorbilidad

Bisero, Elsa; Luque, Graciela; Rizzo, Cristina N; Zapata, Alejandra; Cuello, María S

doi:10.5546/aap.2016.e233

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…24 , 25 Unconventional, potentially invasive testing for TB should not be delayed in HSCT recipients. 1 , 26 , 27 …”

Section: Discussionmentioning

confidence: 99%

<p>Identification and Treatment of Tuberculosis in Pediatric Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: Case Series and Review of the Literature</p>

Wang

et al. 2020

IDR

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Background: Tuberculosis is a rare but life-threatening complication in patients who received hematopoietic stem cell transplantation. Early identification and intervention are essential to prevent severe complications. Case Presentation: We report two pediatric patients who developed tuberculosis after receiving hematopoietic stem cell transplantation for thalassemia major among 330 recipients between January 2012 and August 2019. Patient A presented with pulmonary tuberculosis and patient B presented with lymph node tuberculosis mimicking post-transplantation lymphoproliferative disorder associated with Epstein-Barr virus reactivation. Patient B's condition was deteriorated, and shortly after the initiation of anti-tuberculosis therapy, the patient was found to have disseminated pulmonary tuberculosis. Patient B was also found to have tuberculous granulomas, an uncommon manifestation of tuberculosis causing severe airway obstruction. Both patients developed critical respiratory failure and required mechanical ventilation; however, they recovered with almost full resolution of pulmonary lesions after multiple treatment adjustments. Conclusion: Tuberculosis must be carefully evaluated in all pediatric patients that receive hematopoietic stem cell transplantation, regardless of the identification of other pathogens. Prophylactic tuberculosis therapy should be considered for high-risk pediatric hematopoietic stem cell transplantation recipients from tuberculosis-endemic regions.

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“…24 , 25 Unconventional, potentially invasive testing for TB should not be delayed in HSCT recipients. 1 , 26 , 27 …”

Section: Discussionmentioning

confidence: 99%

<p>Identification and Treatment of Tuberculosis in Pediatric Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: Case Series and Review of the Literature</p>

Wang

et al. 2020

IDR

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“…Early diagnosis of actinomycosis can be difficult and patients were often misdiagnosed with fungal or Mycobacterium tuberculosis infections based on clinical presentations and conventional imaging techniques [[2], [3], [4]]. In addition, co-infection of other pathogens such as Mycobacterium tuberculosis could worsen the progression of disease [5]. Our report suggests that patients with thalassemia major are risk of opportunistic infections.…”

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confidence: 99%

Asymptomatic actinomycosis in a girl with thalassemia major

Wang

2019

IDCases

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We present a rare case of lung actinomycosis in a girl with thalassemia major with a competent immunological status. Chest computed tomography scans showed high intensity nodules in the right lower lung. Diagnosis was confirmed by revealing of actonomycetes from the staining of bronchoalveolar fluid. The patient was given intravenous penicillin then oral amoxicillin and clavulanate potassium. This patient responded well after antibiotic treatment for four months. Our report suggests that clinicians should evaluate the immune response underlying asymptomatic infections before conducting hematopoietic stem cell transplantations.

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Pseudomicosis por oportunistas: desconocimiento y retos diagnósticos

Garcés-Abad¹,

Cardona-Castro

2021

CES Med

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Se denominan pseudomicosis a las infecciones generadas por microorganismos que parecen hongos pero que no lo son. En esta revisión se abordan desde una perspectiva etiológica, epidemiológica y clínica algunas de las pseudomicosis por oportunistas más frecuentes: actinomicosis, botriomicosis, nocardiosis y prototecosis. Adicionalmente, se revisan las herramientas clínicas y paraclínicas para facilitar su diagnóstico y se actualizan las pautas de tratamiento.

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Tuberculosis y actinomicosis. Un caso pediátrico de comorbilidad

Cited by 4 publications

References 8 publications

<p>Identification and Treatment of Tuberculosis in Pediatric Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: Case Series and Review of the Literature</p>

<p>Identification and Treatment of Tuberculosis in Pediatric Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: Case Series and Review of the Literature</p>

Asymptomatic actinomycosis in a girl with thalassemia major

Pseudomicosis por oportunistas: desconocimiento y retos diagnósticos

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