Tuberculosis situation in Ismailia governorate (2002–2012) before and after Direct Observed Therapy Short Course Strategy (DOTS)

Negm, Medhat F.; mehy, Gehan F. Al; Ali, Tahany M.; Elfadil, Safwa S. Abd

doi:10.1016/j.ejcdt.2015.09.005

Cited by 7 publications

(8 citation statements)

References 5 publications

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“…Age distribution of patients was similar between Lower and Upper Egypt as the highest percentage of cases was between 15 and less than 30 years, and the lowest percentage was for extremes of age less than 15 years and after 60 years. These results are in agreement with many individual Egyptian governorate studies that showed same results [9][10][11][12][13][14][15][16][17][18][19][20][21]. However, in Alexandria, the highest percentage of cases was in the age range 30-45 years [22].…”

Section: Discussionsupporting

confidence: 90%

“…The highest percentage was in males (66.1 and 62.7%, respectively), with statistically significant difference between males and females (Table 2), which was in concordance with most individual governorate studies [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]. This difference may be owing to low notification rates in females as many female patients do not seek medical advice because of factors such as illiteracy and the traditions predominant in the society, which may prohibit them from going out and seeking medical advice.…”

Section: Discussionsupporting

confidence: 83%

“…Those studies explained the higher TB cases in rural areas owing to poverty, drinking contaminated milk, exposure to cough spray from infected cattle, or by close physical contact with infected animals. However, in Sharkia [19] and Ismailia [17], despite the rural population is more than the urban, TB cases were higher in the urban areas, and their explanation for that was the possibility of overcrowding at the urban areas, especially slums with lack of proper aeration and increase of air pollution, whereas the awareness among the rural population about TB especially after implementation of DOTS in all primary healthcare units may be the cause for lower percentage of cases. In Port Said, which is mainly urban governorate, cases were more common among the urban areas.…”

Section: Discussionmentioning

confidence: 95%

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Tuberculosis in Upper and Lower Egypt before and after directly observed treatment short-course strategy: a multi-governorate study

et al. 2019

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Background Tuberculosis (TB) is a major problem in developing countries. TB in Egypt is considered an important public health problem. Egypt is ranked among the mid-level incidence countries. Objective To evaluate TB status in 19 governorates and to compare the TB situation in Upper and Lower Egypt over 20 years from 1992 to 2012 before and after the application of directly observed treatment short-course strategy (DOTS). Patients and methods This is a retrospective study involving record review. The registered data were collected from TB registration units in the 19 governorates. Results The highest percentage of TB cases was in the age group 15-30 years. Infection was higher in males than females and in rural areas more than urban areas. Pulmonary TB and smear positivity at diagnosis, second, third, and fifth month were higher in Lower Egypt. Treatment after failure or relapse was significantly higher in Upper Egypt, whereas default rate, failure rate, and death rate were significantly higher in Lower Egypt. Regarding treatment outcome, cure, complete treatment, and transfer out were significantly increased after DOTS than before. Failure, default, and death were significantly reduced after DOTS than before DOTS. Upper Egypt included higher incidence rates of TB, new adult smear-positive cases, new extrapulmonary TB cases, and sputum conversion rate at the end of the initial phase of treatment. Cure rate and treatment success rate were significantly higher among patients of Upper Egypt, whereas transfer out rate and retreatment failure rate were significantly higher among Lower Egypt patients. Conclusion TB is still a health problem in Egypt, with pulmonary TB more in Lower Egypt, whereas extrapulmonary more in Upper Egypt, but after the introduction of DOTS, there is a significant increase in cure and success rate, with markers of success being more in Upper Egypt.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 95%

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Tuberculosis in Upper and Lower Egypt before and after directly observed treatment short-course strategy: a multi-governorate study

et al. 2019

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“…Riskier occupations such as working in the mines, alcohol abuse and smoking may explain higher TB rates among men, including poor treatment outcomes. [18][19][20] This highlights the need to scale up interventions aimed at improving diagnosis and treatment of TB in men complemented by behaviour and lifestyle change programmes.…”

Section: Resultsmentioning

confidence: 99%

Trends in diagnostic techniques and factors associated with tuberculosis treatment outcomes in Lesotho, 2010–2015

Mugomeri

Bekele

Maibvise

et al. 2017

Southern African Journal of Infectious Diseases

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“…The current first-line treatment strategies for drug-susceptible tuberculosis call for the use of as much as four antimicrobial medications, for a course of 6 months. This can generally attain a cure rate of 85%, and up to 98%, for new drug-susceptible TB cases (2), especially when The Directly Observed Treatment Short-course (DOTS) guidelines are advocated (7).…”

Section: Introductionmentioning

confidence: 99%

Extrapulmonary Tuberculosis is the Leading Presentation among Hospitalized Children: A Single-Center Experience in a Decade

Basanti

El-Saiedi

Moawad

et al. 2021

Pediatric Sciences Journal

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Background: With an incidence of twelve tuberculosis (TB) cases for every 100,000 persons in 2019, Egypt is considered a medium-burden country. Nevertheless, guidelines and studies for admission of pediatric TB cases are lacking in developing countries. Aim of the Work:To describe the clinical presentations of hospitalized pediatric TB cases. Materials and Methods: A retrospective analytical study of data collected from the inpatient medical files of children with confirmed TB, from the archives of Giza Chest Hospital (Omraneya), Egypt was implemented during January 2009 to the end of 2018. Results: Of the 76 children hospitalized with TB, 42 were males with a male to female ratio of 1.2:1, 61 (80.3%) patients were from rural areas, and 65 (85.5%) were above six years of age. Extra-pulmonary TB was more common (45 patients; 59.2%) than pulmonary TB (31 patients; 40.8%). Tuberculous LN affection was (N=20) 26.2% of total patients, followed by pleural affection (N=17), then affection of bones (N=4). CNS involvement was among least common presentations (N=4; 5.3%), but was the only type of TB to occur more in preschool children. Moreover, there was an annual rate of change of -2.714 in the recorded numbers of pediatric TB inpatients with no cases in the last two years. Conclusion: Extra-pulmonary TB was more common than pulmonary TB among the hospitalized children. Lymph nodes were the most common extra-pulmonary site of affection. School-aged children were a majority as well as rural residents. These findings warrant evoking awareness among physicians about the various presentations of pediatric TB.

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Tuberculosis situation in Ismailia governorate (2002–2012) before and after Direct Observed Therapy Short Course Strategy (DOTS)

Cited by 7 publications

References 5 publications

Tuberculosis in Upper and Lower Egypt before and after directly observed treatment short-course strategy: a multi-governorate study

Tuberculosis in Upper and Lower Egypt before and after directly observed treatment short-course strategy: a multi-governorate study

Trends in diagnostic techniques and factors associated with tuberculosis treatment outcomes in Lesotho, 2010–2015

Extrapulmonary Tuberculosis is the Leading Presentation among Hospitalized Children: A Single-Center Experience in a Decade

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