Tuberculosis mimicking metastases by malignancy in FDG PET/CT

Liu, B.; Dong, Lihua; Wang, X.; Han, Tao; Lin, Qiao; Liu, M.

doi:10.1093/qjmed/hcw214

Cited by 7 publications

(5 citation statements)

References 6 publications

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“…Also, the radiological appearances of tuberculosis and malignancy are very similar, thus increasing the confusion for diagnosis (Xiang et al 2021). Pott's spine is a known common differential for lytic skeletal metastases (Liu et al 2017;Ye et al 2016;Go et al 2012), and nonspecific uptake of F-18 FDG in active infection and inflammation reduces its specificity. The typical radiological features of Pott's spine include anterior destruction of vertebral body, end plate erosions, loss of disc height, paravertebral masses and contiguous multivertebral involvement (Rivas-Garcia et al 2013).…”

Section: Discussionmentioning

confidence: 99%

Necrotizing granulomatous inflammation mimicking skeletal metastasis: a possible differential diagnosis

Datta

Ravichandran

Kumar

et al. 2022

European J Hybrid Imaging

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Tuberculosis is an endemic disease in India for decades, and its coexistence in the patients with malignancy cannot be ignored. The non-specific uptake of 2-deoxy-2-[fluorine-18] fluoro-d-glucose in active infection and malignancy can affect the diagnosis and management of patients. However, characteristic anatomical features of the lesion aid not only in its localization but also in diagnosis. We share an interesting case of necrotizing granulomatous inflammation of dorsal spine mimicking skeletal metastases in a treated case of carcinoma cervix.

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Section: Discussionmentioning

confidence: 99%

Necrotizing granulomatous inflammation mimicking skeletal metastasis: a possible differential diagnosis

Datta

Ravichandran

Kumar

et al. 2022

European J Hybrid Imaging

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“…PET scan lacks the specificity and inability to differentiate granulomatous from malignant involvement based on standardized uptake values. The median uptake value for lymph node is 6.5 (range 3.4–9.2) for tuberculosis and 8.0 (range 2.5–20.1) for malignancy 17,18 . Therefore, pathologic confirmation is vital for accurate staging.…”

Section: Methodsmentioning

confidence: 99%

“…15 The recommendations related to EBUS following CT and PET scan have been enumerated in for malignancy. 17,18 Therefore, pathologic confirmation is vital for accurate staging.…”

Section: Staging and Diagnosis Of Cancermentioning

confidence: 99%

Clinical management of stage III non‐small cell lung cancer in India: An expert consensus statement

Batra

Prabhash

Agarwal

et al. 2023

Asia-Pac J Clncl Oncology

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Non‐small cell lung cancer (NSCLC) is considered the most common type of lung cancer (>80% of all lung cancers); patients are often diagnosed at advanced stages of the disease. The management of NSCLC is considered challenging owing to variations in size, an extension of the tumors, involvement patterns, and classification. Although adequate literature and guidelines are available on the management of NSCLC in several countries, an Indian perspective on stage III NSCLC management is lacking. We used the modified Delphi approach to form consensus statements. A thorough literature search was done. The authors then convened and deliberated over published literature, available guidelines, and clinical judgment. Recommendation statements were formed for different clinical scenarios. These statements were sent as a form of survey to other oncologists, and their responses were recorded and mentioned. Evidence‐based statements were formed for diagnosing and managing stage III NSCLC. These recommendation statements cover various aspects—surgical, radiation, and medical treatment in various clinical scenarios including adjuvant, neoadjuvant, and consolidation therapies.

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“…Radiological as well as nuclear imaging modalities have fallacies when differentiating between granulomatous, reactive and malignant nodes 15 . The role of PET-CECT is established but it has lower sensitivity in non-enlarged nodal disease compared to grossly enlarged nodes 16 .…”

Section: Assessment Of Para-aortic Lymph Node (Paln)mentioning

confidence: 99%

Para-aortic lymph node involvement in cervical cancer: Implications for staging, outcome & treatment

2021

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Tuberculosis mimicking metastases by malignancy in FDG PET/CT

Cited by 7 publications

References 6 publications

Necrotizing granulomatous inflammation mimicking skeletal metastasis: a possible differential diagnosis

Necrotizing granulomatous inflammation mimicking skeletal metastasis: a possible differential diagnosis

Clinical management of stage III non‐small cell lung cancer in India: An expert consensus statement

Para-aortic lymph node involvement in cervical cancer: Implications for staging, outcome & treatment

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