Tuberculosis in pregnant women and neonates: A meta-review of current evidence

Abstract

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A pregnant woman with pre-XDR PTB giving birth to a healthy newborn: A case report

“…Clinical diagnosis of neonatal TB depends on symptoms, imaging results, possible exposure history and response to treatment [ 5 , 6 ]. Although there is evidence that early detection and treatment of maternal drug-sensitive TB could protect fetuses and newborns from congenital TB and preterm birth, clinicians could be confused by drug-resistant TB because of the high side effects of drugs and the lack of evidence-based medical evidence for the use of pregnant women [ 7 , 8 ]. In this report, we describe a woman in the third trimester who was diagnosed with pre-extensively-drug resistant pulmonary tuberculosis (pre-XDR PTB).…”

Untitled

“…Latent tuberculosis infection has affected around 900 million women throughout the world [1], where it is estimated that there are as much as 216,500 cases of latent TB infection per year [2]. Latent TB infection during pregnancy has a high risk of developing into an active TB infection.…”