Tuberculosis in patients with end-stage renal disease

Andrew, O.T.; Schoenfeld, Patricia Y.; Hopewell, Philip C.; Humphreys, Michael H.

doi:10.1016/0002-9343(80)90166-7

Cited by 228 publications

(116 citation statements)

References 18 publications

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“…[5,14,23] However, different HD centers from Turkey reported that pulmonary TB was more frequent among dialysis patients (61-70%). [16,17,24] In contrast to these previous studies from Turkey, [17,24] nonpulmonary TB (n = 14, 66.6%) was dominant among our patients with TB.…”

Section: Discussionmentioning

confidence: 99%

“…[3] End-stage renal failure (ESRF) is an immunocompromising condition that is associated with an increased incidence of TB. [4,5] The diagnosis of TB may be complicated and difficult in patients with ESRF requiring dialysis because of impaired immune functions, atypical clinical presentation, nonspecific symptoms and signs that may be attributable to uremia, and a higher occurrence of extrapulmonary TB. ESRF is associated with cutaneous anergy, resulting from immune deficiency, which can result in a false-negative tuberculin skin test (TST).…”

Section: Introductionmentioning

confidence: 99%

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The Prevalence and the Characteristics of Tuberculosis Patients Undergoing Chronic Dialysis Treatment: Experience of a Dialysis Center in Southeast Turkey

Kayabaşı¹,

Şit²,

Kadiroglu³

et al. 2008

Renal Failure

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Prevalence and the Characteristics of Tuberculosis Patients Undergoing Chronic Dialysis Treatment: Experience of a Dialysis Center in Southeast Turkey

Kayabaşı¹,

Şit²,

Kadiroglu³

et al. 2008

Renal Failure

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“…The details of the 10 cases examined by QFT-2G are listed in Table 5 Previous studies reported a high frequency of cases of TB discovered in the first year of dialysis (3,4,13,19 HD (HD >1 year) T a b l e 3 . Ra d i o l o g i c a l Cl a s s i f i c a t i o n o f 1 6 P a t i e n t s wi t h P u l mo n a r y T u b e r c u l o s i s …”

Section: Qft-2gmentioning

confidence: 99%

Active Tuberculosis in Patients Undergoing Hemodialysis for End-stage Renal Disease: A 9-year Retrospective Analysis in a Single Center

et al. 2009

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Objective Tuberculosis (TB) (HR 8.86, p=0.04), and underweight (HR 10.88, p=0.02). The sensitivity of and polymerase chain reaction was 50, 80, and 88.2% years from the initiation of dialysis. Most patients presented with fever (84.2%) and extrapulmonary TB (57.9%). The mortality rate within 24 weeks of the initiation of TB treatment was 36.8%. The factors associated with mortality were: a short duration of dialysis

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“…That is, while the incidence may range between 1.6% to 5.8% in developed countries [3], in developing countries such as Turkey it may be as high as 23.6% [4].…”

Section: Introductionmentioning

confidence: 99%

Tuberculosis in dialysis patients: a nine-year retrospective analysis

Ünsal

Ahbap

Baştürk

et al. 2013

J Infect Dev Ctries

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Introduction: Diagnosis of tuberculosis (TB) among dialysis patients may be difficult because of increased frequency of extra-pulmonary presentations, atypical clinical manifestations, and non-specific symptoms. This study aimed to investigate the spectrum of clinical presentations and outcome in dialysis patients during a nine-year period. Methodology: A total of 651 patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) for at least three months in our unit between 2001 and 2010 were studied. Dialysis and follow-up were performed in our tertiary care center located in the eastern region of Turkey. Diagnosis of TB was established by combining clinical, radiological, biochemical, microbiological, and histological findings. Choice of anti-TB drug used, the results of therapy, and patient outcome were noted. Results: Out of 651 dialysis patients studied, 322 (49.4%) were on PD and the remainder on HD (50.6%). Twenty-six (4%) of the 651 dialysis patients were diagnosed with TB (15 PD, 11 HD), 5 of whom were diagnosed by microbiological assessment, 9 by pathological assessment, and 12 by clinical and radiological findings. Mean age at diagnosis was 41.5 ± 16.5 years and the female/male ratio was 1.18. Three patients had a history of pulmonary TB. Extra-pulmonary involvement was observed in 17 (65.4%) patients. All patients were treated with rifampicin isoniazid, ethambutol, pyrazinamide and pyridoxine. Four patients died during the study. Conclusion: TB occurred in dialysis patients and extra-pulmonary TB was more commonly identified than pulmonary TB. Tuberculous lymphadenitis was the most frequent form of extra-pulmonary TB in our cohort.

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Tuberculosis in patients with end-stage renal disease

Cited by 228 publications

References 18 publications

The Prevalence and the Characteristics of Tuberculosis Patients Undergoing Chronic Dialysis Treatment: Experience of a Dialysis Center in Southeast Turkey

The Prevalence and the Characteristics of Tuberculosis Patients Undergoing Chronic Dialysis Treatment: Experience of a Dialysis Center in Southeast Turkey

Active Tuberculosis in Patients Undergoing Hemodialysis for End-stage Renal Disease: A 9-year Retrospective Analysis in a Single Center

Tuberculosis in dialysis patients: a nine-year retrospective analysis

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