Tuberculosis in Home-Contacts: A Note on Incidence and the Role of Human Contagion

Kayne, G. Gregory

doi:10.1136/bmj.1.3874.692

BMJ

1935

DOI: 10.1136/bmj.1.3874.692

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Tuberculosis in Home-Contacts: A Note on Incidence and the Role of Human Contagion

G. Gregory Kayne¹

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1937

1964

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Cited by 2 publications

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“…(1) infants known to us since the time of their birth; (2) infants not known to us since birth who gave a negative reaction to the tuber¬ culin test at the time of their admission to the study, and (3) infants known to us for less than their whole lives who gave a positive reaction to the tuberculin test when we first saw them. Only the first two of these groups were used as controls in the B C G study, and the chil¬ dren of the third group were observed merely as an especially interest¬ ing series.…”

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confidence: 99%

Fate of Children Infected With Tuberculosis During the First Five Years of Life

Rosenberg¹,

Kereszturi²

1937

Arch Pediatr Adolesc Med

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There is increasingly less pessimism concerning the fate of children infected with tuberculosis during infancy. The reason for this change lies partly in the progressively improving ability of the medical profession to diagnose mild and subclinical tuberculosis in infants and young children. Before the discovery of the tuberculin test and the roentgen rays, only those infants who presented clinical signs were regarded as tuberculous. The prognosis of such infants was and still is grave. However, apparently well children whose only sign of tuberculous infection is a positive reaction to the tuberculin test or an abnormal appearance of the lungs in a roentgenogram of the chest are now known. They really belong in a different category than do the clinically ill children and have a much better prognosis. Since the term tuberculous infants is used for both types of patients and since the recent literature more frequently deals with the subclinical type, the impression of an improving prognosis for tuberculosis in infants is created.However, even if one allows for the difference in the type of the tuberculous patients with which the recent literature deals, the course of tuberculous infection in children at present appears to be mild more frequently than in the past. It is probable that because of improved technic in diagnosis more persons who are sources of infection are recognized early now than in former years. Early diagnosis involves early precautions and measures for the prevention of the spread of the disease. It is reasonable to assume that fewer infants than for¬ merly are now exposed to massive doses of tubercle bacilli.It may be inferred, therefore, that the milder tuberculous infections and the greater number of early and subclinical diagnoses among infants are responsible for the apparently lower rate of deaths from tubercu¬ losis among infants and children reported in the recent medical litera¬ ture. If one could compare strictly analogous types of tuberculous infants of half a century ago and of the present, the difference in Downloaded From: http://archpedi.jamanetwork.com/ by a University of Michigan User on 06/21/2015

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mentioning

confidence: 99%

Fate of Children Infected With Tuberculosis During the First Five Years of Life

Rosenberg¹,

Kereszturi²

1937

Arch Pediatr Adolesc Med

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An attempt to determine the background to pulmonary tuberculosis in adolescent males (based on a military survey)

Boyd

1964

British Journal of Diseases of the Chest

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Tuberculosis in Home-Contacts: A Note on Incidence and the Role of Human Contagion

Cited by 2 publications

References 4 publications

Fate of Children Infected With Tuberculosis During the First Five Years of Life

Fate of Children Infected With Tuberculosis During the First Five Years of Life

An attempt to determine the background to pulmonary tuberculosis in adolescent males (based on a military survey)

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