Tuberculosis in children treated with second-line drugs under programmatic conditions in Lima, Peru

Abstract

To characterise childhood tuberculosis (TB) treated with second-line drugs (SLDs) in Lima, Peru. D E S I G N : Results for the age groups ,5 and 5-14 years were compared and treatment outcomes were assessed in cases reported between 2011 and 2015 from six districts of Lima. R E S U LT S : Of 96 reported cases, 82 were evaluated. Among these, 59% were boys; the median age was 8 years and 32% were aged ,5 years. Contact with a TB case was reported in 82% of cases; 90% were treatmentnaïve, 98% had pulmonary localisation and 50% underwent the tuberculin skin test (purified protein derivative), with induration 710 mm in 88%. A positive smear was found in 40%, all in the 5-14 years age This was an operational research study using a retrospective cohort design.