1992
DOI: 10.1001/jama.268.12.1581
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Tuberculosis and HIV infection in sub-Saharan Africa

Abstract: The epidemiology of tuberculosis has been profoundly influenced by the epidemic of HIV infection in sub-Saharan Africa. Greatly increased human and material resources are required for this neglected problem in international health.

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Cited by 293 publications
(51 citation statements)
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“…105 The risk of TBM may be greater in HIV-positive individuals with TB, 106 but it is unclear whether cerebral infarcts are more common. 107,108 Whilst some maintain that HIV infection does not alter the clinical or radiological manifestations or the outcome, of TBM, 106,109 others report higher mortality, more basal meningeal enhancement and more frequent obstructive hydrocephalus in HIV-positive TBM.…”
Section: The Influence Of Hivmentioning
confidence: 99%
“…105 The risk of TBM may be greater in HIV-positive individuals with TB, 106 but it is unclear whether cerebral infarcts are more common. 107,108 Whilst some maintain that HIV infection does not alter the clinical or radiological manifestations or the outcome, of TBM, 106,109 others report higher mortality, more basal meningeal enhancement and more frequent obstructive hydrocephalus in HIV-positive TBM.…”
Section: The Influence Of Hivmentioning
confidence: 99%
“…Tuberculosis (TB) is the most common HIV-related opportunistic infection (OI) (UN-AIDS, 2003;De Cock, Soro, Coulibal, & Lucas, 1992). It is estimated that up to 70% of TB patients in the African setting are co-infected with HIV (Raviglione, Harries, Msiska, Wilkinson, & Nunn, 1997;Harries, Nyangulu, & Kang'ombe, 1998).…”
Section: Introductionmentioning
confidence: 99%
“…As a general principle, the more immunosuppressed the host, the more extreme these differences are [88]:…”
Section: Clinical Aspects Of Tb Disease In the Hiv-infected Patientmentioning
confidence: 99%