Tuberculosis, AIDS and tuberculosis-AIDS co-infection in a large city

Saita, Nânci Michele; Oliveira, Helenice Bosco de

doi:10.1590/s0104-11692012000400018

Cited by 7 publications

(8 citation statements)

References 13 publications

(15 reference statements)

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“…Regarding clinical factors, our analysis confirms many earlier reports [ 4 , 6 , 10 , 16 , 27 ] of the strong association between HIV co-infection and extrapulmonary TB. In a Brazilian study on TB-HIV coinfection between 2006 and 2010, EPTB occurred in 26.2% of HIV-infected patients [ 28 ].…”

Section: Discussionsupporting

confidence: 90%

“…Two studies at the national level mention EPTB only when discussing TB in persons co-infected with human immunodeficiency virus (HIV) [ 4 , 5 ]. Studies have addressed EPTB at the level of states [ 6 ], municipalities [ 4 , 7 ], and healthcare services [ 5 , 8 ] in Brazil, but none have addressed it at the national level. This situation is illustrated by the omission of EPTB from the latest epidemiological report on TB by the Brazilian Health Ministry published in 2012 [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…The rate of EPTB in Brazil increased from 6.8 per 100,000 people in 1981 to 7.0 per 100,000 people in 1991. A study conducted in the municipality of Campinas, São Paulo between 2001 and 2009 found a 23.7% reduction in the number of cases of pulmonary TB (PTB) but only a 5.9% reduction in the number of cases of EPTB [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

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Epidemiology of extrapulmonary tuberculosis in Brazil: a hierarchical model

et al. 2014

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BackgroundAlthough extrapulmonary tuberculosis (EPTB) is less frequent than Pulmonary Tuberculosis (PTB) and is a secondary target for national TB control programs, its significance has increased worldwide during the HIV epidemic. The objective of this study was to examine the epidemiology of EPTB in Brazil between 2007 and 2011.MethodsCross-sectional study involving all cases of TB reported to the Brazilian Notifiable Diseases Surveillance System (Sistema de Informações de Agravo de Notificação - SINAN) in Brazil between 2007 and 2011. Sociodemographic and clinical characteristics of patients with exclusively PTB and exclusively EPTB were compared. Following analysis with Pearson’s chi-square test, variables with p < 0.05 were included in a hierarchical regression model. Variables with p < 0.05 in the corresponding level were kept in the model.ResultsA total of 427,548 cases of TB were included. Of these, 356,342 cases (83.35%; 95% confidence interval (CI) 83.23% - 83.45%) were PTB, 57,217 (13.37%; 95% CI 13.28% - 13.48%) were EPTB, 13,989 (3.27%; 95% CI 3.21% - 3.32%) were concurrent pulmonary and extrapulmonary TB. Patients with EPTB were mainly white (16.7%), and most (29.1%) patients had five to eight years of education. Among comorbidities, HIV infection was prominent (OR 2.15; 95% CI 2.09 – 2.21), although the proportion of cases awaiting test results or untested was high (39%). Ethanol use (OR 0.45; 95% CI 0.43 – 0.46), diabetes mellitus (OR 0.54; 95% CI 0.51 – 0.57) and mental illness (OR 0.88; 95% CI 0.82 – 0.95) were associated with PTB.ConclusionsThirteen percent of patients diagnosed with TB in Brazil have only EPTB. More effective diagnostic strategies and control measures are needed to reduce the number of cases of extrapulmonary TB in Brazil.

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Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

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Epidemiology of extrapulmonary tuberculosis in Brazil: a hierarchical model

et al. 2014

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“…A similar co-infection percentage has been seen in a Rio de Janeiro hospital cohort 7 . Studies in Southeast region point to a 34.5% AIDS-tuberculosis co-infection prevalence in Belo Horizonte, MG, 52.5% in São José do Rio Preto, SP, 17.5% in Campinas, SP, and 14.5% in Vitória, ES 25,[31][32][33] .…”

Section: Discussionmentioning

confidence: 99%

Sobrevida de pacientes com AIDS e coinfecção pelo bacilo da tuberculose nas regiões Sul e Sudeste do Brasil

Melo

Donalísio

Cordeiro

2017

Ciênc. saúde coletiva

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The study investigates the survival of patients with co-infection AIDS-TB through a retrospective study of a cohort of individuals aged 13 or more and the diagnosis of AIDS reported in the years 1998-99 and following 10 years. Of the 2,091 AIDS cases, 517 (24.7%) had positive diagnosis for tuberculosis, and 379 (73.3%) were male. The risk among co-infected patients was 1,65 times the not co-infected. Have been compared the exposed and non-exposed through the Kaplan-Meier and Cox method. The variables associated with longer survival were: female gender (HR = 0.63), educational level ≥ eight years (HR = 0.52), CD4 diagnostic criteria (HR = 0.64); and shorter survival: age ≥ 60 years (HR = 2.33), no use of HAART (HR = 8.62), no investigation to Hepatitis B (HR = 2.44) and opportunistic infections ≥ two (HR = 1.97). The average survival rate, related to TB infection was 69 months for the Southeast region and 73 months for the South. AIDS and tuberculosis require monitoring and treatment adherence and they are markers of the quality of care and survival of patients in Brazil.

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“…Dentre os participantes, 72,2% eram do sexo masculino, resultado que encontrado em outros estudos que apresentam que a população masculina é maior que a feminina (DOMINGOS et al, 2008;SAITA;OLIVEIRA, 2012;SANTOS NETO et al, 2012).…”

Section: Análise Dos Dadosunclassified

Prevalência da coinfecção HIV/tuberculose em indivíduos residentes no município de Ribeirão Preto - SP

Castrighini¹

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Vania pelo amor incondicional, pelo carinho, dedicação e compreensão em todos os momentos, por me incentivarem nas dificuldades. Obrigada por estarem sempre ao meu lado. Ao meu grande amor Marcos Aurélio Marcos Aurélio Marcos Aurélio Marcos Aurélio, meu amigo, que sempre me escutou nos momentos mais difíceis. Obrigada pela compreensão, pelo amor e cumplicidade. Ao meu querido irmão Jorge Jorge Jorge Jorge, por sempre fazer parte da minha vida, pela amizade e carinho. Obrigada pelo amor que sempre nos uniu. Ao meu avô Adejair Adejair Adejair Adejair, Deja Deja Deja Deja, por seu exemplo de superação, por ser um guerreiro e me ensinar a não fraquejar diante das dificuldades. Obrigada por permitir que eu me lembre de você todos os dias. Você foi a razão para eu continuar. A Deus Deus Deus Deus por me conceder o dom da vida e por permitir que eu buscasse nEle forças nos momentos mais difíceis. Obrigada por me conceder tantas conquistas. Agradecimentos especiais Agradecimentos especiais Agradecimentos especiais Agradecimentos especiais À Profª Drª Elucir G Elucir G Elucir G Elucir Gir ir ir ir, pela amizade, por acreditar em mim desde o início, por ter dedicado seu tempo a me ensinar. Obrigada pelos conselhos e pela compreensão. Que Deus possa retribuir todo o carinho que você teve comigo durante minha trajetória.

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Tuberculosis, AIDS and tuberculosis-AIDS co-infection in a large city

Cited by 7 publications

References 13 publications

Epidemiology of extrapulmonary tuberculosis in Brazil: a hierarchical model

Epidemiology of extrapulmonary tuberculosis in Brazil: a hierarchical model

Sobrevida de pacientes com AIDS e coinfecção pelo bacilo da tuberculose nas regiões Sul e Sudeste do Brasil

Prevalência da coinfecção HIV/tuberculose em indivíduos residentes no município de Ribeirão Preto - SP

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