Tuberculose ganglionnaire: aspects épidémiologiques, diagnostiques et thérapeutiques, à propos de 357 cas

Hamzaoui, G.; Àmro, L.; Sajiai, H.; Serhane, H.; Moumen, N.; Ennezari, Abdellah; Yazidi, A. Alaoui

doi:10.11604/pamj.2014.19.157.4916

Cited by 8 publications

(10 citation statements)

References 7 publications

(13 reference statements)

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“…The lymphadenopathies involved mostly the transversal cervical chain (55.8%), spinal chain (50%), and jugulocarotidian chain (32.4%). These results are similar to those of the literature, which reported the LNTB mostly to be localized to the anterior or posterior cervical chains (70-90%) [7,12,18]. The LNTB is often bilateral, and noncontiguous lymph nodes can also be involved [3].…”

Section: Discussionsupporting

confidence: 91%

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Lymph Node Tuberculosis in Otolaryngological Practice: A Study of 68 Cases at the Sourô Sanou University Hospital of Bobo Dioulasso, Burkina Faso

Ouedraogo

Amona

Atonoboma

et al. 2022

ORL

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Introduction: Lymph node tuberculosis (LNTB) frequently affects peripheral cervical lymph node body sites. We aimed to study epidemiology and diagnostic and therapeutic characteristics of LNTB patients in ENT routine practice. Methods: We conducted a cross-sectional prospective study in the ENT and cervicofacial surgery department at the Sourô Sanou University Hospital of Bobo Dioulasso, Burkina Faso, for a period of 36 months. Results: There were 68 cases with LNTB, of which 54.4% were mostly men. The mean age and the median age were calculated at 37 ± 6.8 and 42 years, respectively. The patient’s age ranged between 3 and 81 years, and the most represented age group was from 30 to 60 years (62%). According to geographical origin, most patients (79%) originated from rural areas. In 6 cases (9%), patients reported diabetes and 12 patients were HIV positives (18%). Most clinical features leading to the ENT consultation were cervical lymph nodes (82%) and cervical scrofuloderma (18%). For the multiple locations, the lymphadenopathies involved mostly the transversal cervical chain (56%) and spinal chain (50%). Histopathology examination was the mostly diagnosed methods used in 68%. A 6-month anti-tuberculous treatment was given with a follow-up of 6 months without any relapse in 62 cases (97%). Conclusion: The frequency of 68 cases of LNTB in 3 years is underappreciated. Among all lymph node sites, transversal cervical chain and cervical spinal chain were mostly affected. Further advanced studies are recommended to determine the prevalence and contributing factors of LNTB in the study area.

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Section: Discussionsupporting

confidence: 91%

“…Although no particular underlying diseases were found in 38 cases (55.9%), 6 patients (8.8%) had diabetes and 12 patients (17.7%) were HIV positive. Similarly, Hamzaou et al [18] reported 9% and 3.6% cases of diabetes and HIV infection, respectively. Also, Benjelloun et al [19] reported 1 patient to have diabetes.…”

Section: Discussionmentioning

confidence: 85%

Lymph Node Tuberculosis in Otolaryngological Practice: A Study of 68 Cases at the Sourô Sanou University Hospital of Bobo Dioulasso, Burkina Faso

Ouedraogo

Amona

Atonoboma

et al. 2022

ORL

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“…With respect to the topography, cervical lymph nodes were the most frequent in our series (86%). This tendency was also reported by various other authors [ 5 , 17 , 18 ]. This could be explained by the anatomical position and physiological role of the jugular-carotid lymph node chain being more accessible compared to the respiratory tract.…”

Section: Discussionsupporting

confidence: 89%

Pathology of lymph node tuberculosis in Yaounde: diagnostic agreement based on the Kappa coefficient

Jmm¹,

Ateba²,

Cjn³

et al. 2018

Pan Afr Med J

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IntroductionLymph node tuberculosis remains widespread in Cameroon. Our goal was to compare the diagnostic agreement between the hematein-eosin coloration technique and the Ziehl-Neelsen technique.MethodsThis study is a retrospective and comparative study realized in the Yaounde University Teaching Hospital over a period of 5 years. We needed to specify the diagnostic agreement for tuberculosis, first inter observer and secondly between the standard and special colorations. The data we collected allowed us to determine the agreement rates observed and the kappa (k) coefficients with linear weighting.ResultsThe 186 samples of the 1726 cases of tuberculosis of all locations represented a proportion of 10.78%. There were more male patients (65.05%) with a sex ratio (M:F) of 1.30. The average age was 24.21 ± 15.5 with the extremes from 5 to 68 years. The most represented age group was from 10 to 39 years. The two observers agreed in 93 cases using hematein eosin coloration (P0 = 83.87 %; k = 0.8109) and on 73 samples using the Ziehl-Neelsen coloration (P0 = 89.78 %; k = 0.7734). The two coloration techniques presented an agreement on 104 samples (P0 = 88.17 %; k = 0.8783).ConclusionThe routine choice of the hematein eosin coloration technique not paired with the coloration technique of Ziehl-Neelsen can effectively alleviate the program for fighting tuberculosis in an environment of limited resources.

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“…Among the EMR countries, Tunisia has the highest proportion of EPT cases (60%) [1]. In Morocco, EPT accounts for 46% of all TB cases, with lymph node EPT being the most common localization followed by pleural EPT [1,7,10]. Due to the paucibacillary nature of the non-respiratory specimens, diagnosis of EPT remains challenging.…”

Section: Introductionmentioning

confidence: 99%

Performance of GeneXpert MTB/RIF in the diagnosis of extrapulmonary tuberculosis in Morocco

Aainouss¹,

Momen²,

Belghiti³

et al. 2021

Russian Journal of Infection and Immunity

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Tuberculosis (TB), a chronic bacterial disease caused by Mycobacterium tuberculosis, commonly affects the lung but can also affect other parts of the body (extrapulmonary tuberculosis, EPT). A rapid diagnosis is essential to initiate a specific and effective treatment. Although mycobacterial culture remains the gold standard for EPT diagnosis, molecular tools are attracting increasing interest. GeneXpert MTB/RIF, a rapid automated diagnostic test, allows the detection of Mycobacterium tuberculosis as well as mutations in the hot-spot region of the rpoB gene associated with Rifampicin resistance. The present study was performed to evaluate the performance of the GeneXpert MTB/RIF test for the diagnosis of EPT compared to the standard method. This prospective study was conducted on 304 clinical samples collected from 192 patients attending the Laboratory of Mycobacteria and Tuberculosis of Pasteur Institute of Morocco, between 2016 and 2017. Out of the 304 samples, 113 were pleural f luids decontaminated using the Petroff method and 191 were biopsies (78 lymph nodes and 113 pleural biopsies) decontaminated using the Löwenstein method. Mycobacterium tuberculosis detection and identification were performed on all samples using smear microscopy, Löwenstein–Jensen medium culture and the GeneXpert MTB/RIF test. Our results showed that 54.5 (103/189) were men and 45.5% (86/189) were women. The age of patients ranged from 2–78 years and the majority of patients was in the age group 25–45 years. Extrapulmonary samples were derived from lymph nodes, pleural f luids and pleural tissues, with a percentage of 25.66, 37.17 and 37.17%, respectively. Interestingly, the sensitivity of the GeneXpert was 51.4 for all samples and 83.3% for lymph nodes. In conclusion, the present study revealed that the performance of the GeneXpert test depends highly on the type of sample, with a high sensitivity observed for lymph nodes. Additionally, we clearly showed that the GeneXpert MTB/RIF test presents limitations in the diagnosis of pleural TB. Thus, we recommend the coupled use of the GeneXpert MTB/RIF and the conventional techniques for EPT diagnosis.

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Tuberculose ganglionnaire: aspects épidémiologiques, diagnostiques et thérapeutiques, à propos de 357 cas

Cited by 8 publications

References 7 publications

Lymph Node Tuberculosis in Otolaryngological Practice: A Study of 68 Cases at the Sourô Sanou University Hospital of Bobo Dioulasso, Burkina Faso

Lymph Node Tuberculosis in Otolaryngological Practice: A Study of 68 Cases at the Sourô Sanou University Hospital of Bobo Dioulasso, Burkina Faso

Pathology of lymph node tuberculosis in Yaounde: diagnostic agreement based on the Kappa coefficient

Performance of GeneXpert MTB/RIF in the diagnosis of extrapulmonary tuberculosis in Morocco

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