Tuberculin skin test reactivity, anergy, and HIV infection in hospitalized patients

Janis, Eric M.; Allen, David W.; Glesby, Marshall J.; Carey, Lisa A.; Mundy, Linda M.; Gopalan, Ramana; Chaisson, Richard E.

doi:10.1016/s0002-9343(97)89457-0

Cited by 31 publications

(24 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The low rate of positive TST and QFT tests limits evaluation of risk factors associated with test positivity and with discordance between the tests. However, the 8 to 9% rate of LTBI suggested by TST and QFT testing in this study is consistent with that seen in other industrialized populations with low TB prevalence (34)(35)(36), where LTBI treatment is a clinical priority and where QFT testing will be feasible.…”

Section: Discussionsupporting

confidence: 90%

Comparison of an Interferon-γ Release Assay with Tuberculin Skin Testing in HIV-infected Individuals

Luetkemeyer

Charlebois

Flores

et al. 2007

Am J Respir Crit Care Med

179

138

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 90%

Comparison of an Interferon-γ Release Assay with Tuberculin Skin Testing in HIV-infected Individuals

Luetkemeyer

Charlebois

Flores

et al. 2007

Am J Respir Crit Care Med

179

138

View full text Add to dashboard Cite

“…Several studies carried out in Latin American countries demonstrated that tuberculosis infection rates in HIV/AIDS population range from 0 to 25% (15,20,22,26,27). The present study found a 13.9% prevalence of tuberculosis infection in the HIV/AIDS population.…”

Section: Discussionsupporting

confidence: 59%

“…In the literature, low CD4+T cell count is associated with negative tuberculin test (20,26,27). However, monitoring alone is not sufficient for the tuberculosis control; thus, isoniazid preventive therapy is highly recommended (15,18).…”

Section: Discussionmentioning

confidence: 99%

Tuberculin skin testing in HIV-infected patients in Campo Grande, Mato Grosso do Sul State, Brazil

Oliveira

Paniago

Bonecini-Almeida

et al. 2010

J. Venom. Anim. Toxins incl. Trop. Dis

View full text Add to dashboard Cite

A cross-sectional study on HIV/AIDS was carried out in 108 outpatients from the university hospital of the Federal University of Mato Grosso do Sul, Campo Grande, Brazil, from July to December 2008, to investigate latent tuberculosis infection using the tuberculin skin test (TST). The prevalence of positive results was 13.9%. The CD4+ T cell count (p = 0.091) and the diagnosis time (p = 0.010) were statistically significant when compared with TST positivity. In the cohort of HIV/AIDS patients who had latent tuberculosis infection, the median diagnosis time was eight years. Undetectable viral load presented significant association (p = 0.046) with tuberculosis infection. The fact that numerous individuals with HIV/AIDS infection presented a negative reaction to the tuberculin skin test is probably related to alterations in the cellular immune response induced by HIV infection. The tuberculin test is a useful tool for the detection of latent tuberculosis infection and should be performed in all HIV/AIDS individuals at the time of the diagnosis and on a yearly basis, if negative. Both the early identification of the tuberculosis infection by the tuberculin skin test at the moment of immunological restoration and chemoprophylaxis in infected individuals are mechanisms to control HIV/AIDS and tuberculosis coinfection

show abstract

“…Janis et al believed that tuberculin testing and anergy testing with other antigens like candida, trichophyton, tetanus toxoid, proteus, diphtheria, etc should be done in all HIV cases and those who are anergic to both are at greater risk of developing tuberculosis [11]. On the other hand some authors have concluded that TST has a limited value in populations with high seropositivity for HIV [12][13][14].…”

Section: Discussionmentioning

confidence: 99%

Significance of Tuberculin Testing in HIV Infection: An Indian Perspective

Sawhney¹

2006

Medical Journal Armed Forces India

View full text Add to dashboard Cite

Tuberculin skin test reactivity, anergy, and HIV infection in hospitalized patients

Cited by 31 publications

References 31 publications

Comparison of an Interferon-γ Release Assay with Tuberculin Skin Testing in HIV-infected Individuals

Comparison of an Interferon-γ Release Assay with Tuberculin Skin Testing in HIV-infected Individuals

Tuberculin skin testing in HIV-infected patients in Campo Grande, Mato Grosso do Sul State, Brazil

Significance of Tuberculin Testing in HIV Infection: An Indian Perspective

Contact Info

Product

Resources

About