TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology

Stoupa, Athanasia; Adam, Frederic; Kariyawasam, Dulanjalee; Strassel, Catherine; Gawade, Sanjay; Szinnai, Gabor; Kauskot, Alexandre; Lasne, Dominique; Janke, Carsten; Natarajan, Kathiresan; Schmitt, Anja; Bôle‐Feysot, Christine; Nitschké, Patrick; Léger, Juliane; Jabot–Hanin, Fabienne; Torès, Frédéric; Michel, A; Münnich, Arnold; Besmond, Claude; Scharfmann, Raphael; Lanza, François; Borgel, Delphine; Poalk, M; Carré, Aurore

doi:10.1530/ey.16.3.12

Cited by 5 publications

(5 citation statements)

References 23 publications

(24 reference statements)

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“…Consequently, sheep and cows could have an important role on HEV transmission in this setting (Modiyinji et al, 2021b). On the other hand, poor sanitation in most African slaughterhouses could contribute to HEV transmission (Cook et al, 2017), while inadequate knowledge among those working with animal blood and unhygienic practices during meat procedures might play a pivotal role (Agu et al, 2021;Abunna et al, 2022). The absence of proper practices in abattoirs and slaughterhouses has been identified as a determining factor in the spread of infectious pathogens in Africa (Odetokun et al, 2022;Gerken et al, 2023), including HEV (Traoré et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Butchering activity is the main risk factor for hepatitis E virus (Paslahepevirus balayani) infection in southwestern Nigeria: a prospective cohort study

Oluremi,

Casares-Jimenez,

Opaleye

et al. 2023

Front. Microbiol.

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IntroductionPaslahepevirus balayani (Hepatitis E virus; HEV) is an emerging virus that poses as a public health threat. The virus is now reported to be the leading cause of acute viral hepatitis, with a unique impact on African settings. Our aim was to evaluate the prevalence and risk factors for HEV infection in three cohorts (animal handlers, villagers, and students).MethodsA prospective cross-sectional study was carried out on a total of 752 subjects from southwestern Nigeria. In all individuals, anti-HEV IgG and anti-HEV IgM antibodies were evaluated by using ELISA (confirming positive results via immunoblotting), and serum viral RNA was evaluated by using two RT-PCR assays.ResultsThe overall seroprevalence of HEV IgG and HEV IgM was 14.9% (95% CI: 12.5–17.6%) and 1.3% (95% CI: 0.7–2.5%), respectively. We observed the highest seroprevalence among animal contact individuals, with butchers being the population with the highest HEV IgG seroprevalence (31.1%). Similarly, HEV IgM was higher in the animal contact group (2.2%) than in the non-animal contact cohort (0%).DiscussionsViral RNA was not detected in any of the samples. Butchering was significantly associated with higher HEV prevalence. Although all efforts to prevent HEV in Africa have focused on the chlorination of water, our study suggests that most new infections could currently be linked to animal manipulation. Therefore, education and guidelines must be provided in southwest Nigeria to ensure that animal handling and processing methods are safe.

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Section: Discussionmentioning

confidence: 99%

Butchering activity is the main risk factor for hepatitis E virus (Paslahepevirus balayani) infection in southwestern Nigeria: a prospective cohort study

Oluremi,

Casares-Jimenez,

Opaleye

et al. 2023

Front. Microbiol.

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“…Thes students were worse hit by pandemic and need more than remedial classes and regular counsellor (Chen & Ming-Hsiang, 2021). Senior can always guide the juniors with common mistakes or mis-perceptions about hospitality education as many students felt that they did not took training very seriously and lose out on honing their basic skills (Cha et al, 2013). A good thing is that youngster believe that situation will recover much sooner then it is expected and are keeping them ready for it (Shah et al, 2020).…”

Section: Table 10: Choice Of Subject/s Students Want To Include As Co...mentioning

confidence: 99%

Can Covid-19 Guide Stakeholders Towards Future Of Hospitality Education? A Study On Students’ Expectations From Training With Reference To Hotel Management Institutes In Mumbai

Dhoundiyal¹,

Salunke²

2023

pjhas

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Background: Barring few sectors like healthcare, the COVID-19 pandemic had severely affected most of the business. Tourism and hospitality were amongst few industries harshly hit by the pandemic. In hospitality worst affected segment of HR were 'freshers' from hotel management institutes. With literally no experience and limited skills they have very few takers in industry with minimum emoluments in offering. Objectives: The prime objective of this paper is to find out the change in the perceptions of students from hospitality education after COVID-19 pandemic. Methodology: This is survey-based study. The responses were taken twice with same set of respondents, first when peak of second COVID wave was over and it looked that things will be normal in near future and second responses were taken when third COVID wave seemed to be inevitable in India. Total 135 students took part in both the surveys and their responses were recorded for further analysis. Results: Pandemic compelled students to think outside their usual choice of four major revenue producing department to commence their career. Marketing and sales, retail industry, HR and training were their preferred choice. Communication and technical skills, physical fitness, creativity and food safety were the attributes listed by them as essential for hospitality professionals. Further, respondents wanted subjects like personality development and communication skills, hotel specific accounting and marketing operations. HRM as practiced in hotel industry, food safety and hospital catering and investments and trading as core subjects in their syllabi. Conclusion: It is high time that hotel management institutes should shift their approach from four operational departments to other equally lucrative field like marketing and retail.

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“…For example, in [32], CBA was used to analyze the sustainability of bioethanol promotion in Thailand. Many researchers have used CBA as a tool to investigate feasibility in various fields such as food waste management [33], healthcare management [34], and a recycling system for end-of-life tires [35]. In addition, CEA has been applied to many cases in which the monetary value of programs is scarcely estimated, including medicine development and information technology development [36,37].…”

Section: B Economic Evaluation Analysismentioning

confidence: 99%

Impact Analysis of Telecommunications Technology Based on Usage Scenarios: The Case of 5G Low-Latency Technology in V2X

Yoon,

Jang,

Kim

et al. 2023

IEEE Access

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The telecommunications sector has experienced enormous advances with technological evolution, and various alternatives for technology development toward 5G technologies have been proposed. To achieve effective research and development (R&D) management, these alternatives should be evaluated. Although cost-benefit analysis, which can help facilitate a technology with the most benefits and the least costs, is generally applied, technology related to public goods should consider both market and non-market perspectives. Since many telecommunications technologies have social impacts as well as market profitability, e.g., 5G, the economic feasibility analysis of such technologies needs to apply market and non-market approaches. Therefore, this paper presents an R&D impact analysis based on usage scenarios that reflect the characteristics of a telecommunications technology. Accordingly, we investigate how the target technology will be employed in a product or service, what costs and benefits the technology will produce, and what methods can be used to measure the costs and benefits. First, the scenarios are constructed to identify different types of benefits while avoiding the overlaps between them. Detailed guidelines are developed to link the most appropriate methods among various economic-feasibility analyses to assess costs and benefits for each usage scenario. Then, the proposed framework is applied to the case of 5G low-latency technology used in vehicle-to-everything (V2X) and validated. The case study findings indicate that the framework is useful in converting direct and indirect benefits of telecommunications technology into a single economic value and is thus expected to be employed in technology evaluation.INDEX TERMS Technology impact analysis; Technology feasibility analysis; Usage scenario; 5G technology; vehicle-to-everything (V2X)

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TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology

Cited by 5 publications

References 23 publications

Butchering activity is the main risk factor for hepatitis E virus (Paslahepevirus balayani) infection in southwestern Nigeria: a prospective cohort study

Butchering activity is the main risk factor for hepatitis E virus (Paslahepevirus balayani) infection in southwestern Nigeria: a prospective cohort study

Can Covid-19 Guide Stakeholders Towards Future Of Hospitality Education? A Study On Students’ Expectations From Training With Reference To Hotel Management Institutes In Mumbai

Impact Analysis of Telecommunications Technology Based on Usage Scenarios: The Case of 5G Low-Latency Technology in V2X

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