Tu1588 Usefulness of Japan Esophageal Society Classification of Magnified Endoscopy for the Diagnosis of Superficial Esophageal Squamous Cell Carcinoma

Oyama, Tsuneo; Ishihara, Ryu; Takeuchi, Manabu; Hirasawa, Dai; Arima, Miwako; Inoue, Haruhiro; Goda, Kenichi; Tomori, Akihisa; Momma, Kumiko

doi:10.1016/j.gie.2012.03.1234

Cited by 36 publications

(57 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although mapping biopsies may allow for a differentiation between intraepithelial neoplasia and invasive carcinoma, it is questionable whether this sampling method is able to reliably determine the depth of invasion, tumor grade, presence of lymphovascular invasion, or presence extension of neoplasia down the ducts. Magnification endoscopy may support the assessment of the depth of tumor invasion[24]. However, as magnifying endoscopy images were not available in all cases, these were excluded from assessment by the panel.…”

Section: Discussionmentioning

confidence: 99%

Is it justified to ablate flat-type esophageal squamous cancer? An analysis of endoscopic submucosal dissection specimens of lesions meeting the selection criteria of radiofrequency studies

Jansen

Schölvinck

Kushima

et al. 2014

Gastrointestinal Endoscopy

View full text Add to dashboard Cite

Background Endoscopic radiofrequency ablation (RFA) appears a safe and effective treatment for flat-type non-invasive squamous neoplasia of the esophagus. However, if RFA is applied to lesions containing invasive cancer (ESCC) histological features associated with lymph node metastases may remain undetected. In addition, extension of neoplasia down the ducts of esophageal submucosal glands (SMGs) may create a sheltered ‘niche’ beyond the reach of ablation. Objective To determine the RFA eligibility of flat-type ESCC. Design Retrospective analysis of prospectively collected data of ESCC patients. Setting National Cancer Center Hospital, Tokyo, Japan. Patients Patients with flat-type ESCC >3cm removed by endoscopic submucosal dissection (ESD). Interventions Three endoscopists involved in RFA studies in China reviewed endoscopic images to select lesions eligible for RFA. Corresponding ESD resection specimens were histologically examined. Main outcome measurements Presence of poor histological features (i.e. ≥m3-invasion; poor tumor differentiation; or lymphovascular invasion) and the number of involved esophageal SMGs and ducts. Results 65 lesions were included of which 17 (26%) qualified as RFA eligible by RFA endoscopists. Inter-observer agreement for this assessment was poor (κ 0.09). Six of the 17 specimens (35%) showed relevant disease: 4 lesions invaded into the muscularis mucosae of which one also showed lymphovascular invasion; two lesions showed extension of neoplasia into SMGs. Limitations Limited number of cases. RFA eligibility status was based on analysis of still images. Conclusions One third of flat-type ESCC, deemed eligible for RFA, demonstrated histological features that are considered (relative) contraindications for endoscopic treatment. As it appears difficult for endoscopists to identify low-risk ESCC, conservative use of RFA for flat-type ESCC is advocated until long-term follow-up data are available.

show abstract

Section: Discussionmentioning

confidence: 99%

Is it justified to ablate flat-type esophageal squamous cancer? An analysis of endoscopic submucosal dissection specimens of lesions meeting the selection criteria of radiofrequency studies

Jansen

Schölvinck

Kushima

et al. 2014

Gastrointestinal Endoscopy

View full text Add to dashboard Cite

show abstract

“…In an attempt to avoid multiplicity of classification systems and complicated criteria, the Japanese Esophageal Society (JES) proposed a new classification in 2012 (22). In this new system, morphology of IPCL is classified into type A and B based on the presence of abnormality including weaving, dilatation, irregular caliber, and difference in shape (Figures 1,2).…”

Section: Ipcl V1-3 and V N -From Carcinoma In-situ To Submucosal Invamentioning

confidence: 99%

Endoscopic diagnosis and management of early squamous cell carcinoma of esophagus

Yip

Chiu

2017

J. Thorac. Dis.

View full text Add to dashboard Cite

In recent years, diagnosis of early squamous cell carcinoma (SCC) of the esophagus has been increasingly emphasized. Utilization of image enhanced technology such as narrow band imaging (NBI) and magnification endoscopy allowed detailed examination of the esophageal mucosa. Different patterns of intrapapillary capillary loops (IPCL) have been proven to accurately diagnose and predict the depth of invasion of the tumors. In addition, the application of endoscopic submucosal dissection (ESD) has enabled safe en bloc resection of esophageal lesions. Promising results of ESD have been published and ESD is now the standard of therapy in early SCC of esophagus.

show abstract

“…In 2011, a new classification of magnified endoscopy for superficial ESCC was proposed by the Japan Esophageal Society (25), which allows differential diagnosis of ESCC, intraepithelial neoplasia and inflammation. This classification is expected to simplify the diagnosis and evaluation of the depth of invasion of superficial ESCCs.…”

Section: Esophageal Sccmentioning

confidence: 99%

Narrow-band Imaging for the Head and Neck Region and the Upper Gastrointestinal Tract

Kikuchi¹,

Ezoe²,

Morita³

et al. 2013

Japanese Journal of Clinical Oncology

View full text Add to dashboard Cite

Endoscopy is essential for the diagnosis and treatment of cancers derived from the gastrointestinal tract. However, a conventional white-light image has technical limitations in detecting small or superficial lesions. Narrow-band imaging, especially with magnification, allows visualization of microstructure patterns and microvascular patterns on the mucosal surface. These technical breakthroughs enable endoscopists to easily detect small pre-neoplastic and neoplastic lesions and to make a differential diagnosis of these lesions. Appropriate diagnosis with narrow-band imaging contributes to minimally invasive endoscopic resection.

show abstract

Tu1588 Usefulness of Japan Esophageal Society Classification of Magnified Endoscopy for the Diagnosis of Superficial Esophageal Squamous Cell Carcinoma

Cited by 36 publications

References 0 publications

Is it justified to ablate flat-type esophageal squamous cancer? An analysis of endoscopic submucosal dissection specimens of lesions meeting the selection criteria of radiofrequency studies

Is it justified to ablate flat-type esophageal squamous cancer? An analysis of endoscopic submucosal dissection specimens of lesions meeting the selection criteria of radiofrequency studies

Endoscopic diagnosis and management of early squamous cell carcinoma of esophagus

Narrow-band Imaging for the Head and Neck Region and the Upper Gastrointestinal Tract

Contact Info

Product

Resources

About