Tu1408 Risk Factors for Perforation of Endoscopic Submucosal Dissection in Gastric Tumors

Risk factors for serious adverse events associated with multiband mucosectomy in Barrett’s esophagus: an international multicenter analysis of 3827 endoscopic resection procedures

“…We believe that the presence of fibrosis may have played a role in some of the perforation cases. This is supported by multiple studies that have identified the presence of fibrosis as an independent risk factor for perforation after ESD for gastric or colorectal lesions [17,19,21,25]. Therefore, we advise to be careful in performing recurrent-ER when the intended ER zone is fibrotic as a result of prior endoscopic treatment or due to an underlying inflammatory disease.…”

“…To our knowledge, no prior studies have evaluated risk factors for an esophageal perforation after ER for the treatment of BE. However, several studies have been published that focused on risk factors for perforation after ER or endoscopic submucosal dissection (ESD) elsewhere in the gastro-intestinal tract [17][18][19][20][21][22][23][24][25][26]. In none of these studies an increased risk of perforation among females was observed.…”

Endoscopic diagnosis and treatment of upper gastrointestinal tumors

“…However, mean time needed per resected specimen was significantly greater during the first 30 procedures (19.04 ± 2.1 min vs. 11.41 ± 1; P = 0.002). The number of complications in the different groups was comparable (13,11,11, and nine, respectively), and consisted mainly of minor bleedings. A similar calculation using blocks of 20 endoscopic resection procedures showed a significant decrease in mean time per resected specimen after 40 procedures (one-way Anova P = 0.0015).…”

“…They also concluded that complications are associated with poorer prognosis after ESD. Shin et al focused on risks for perforation in 643 patients [11]. Perforation occurred in a total of 65 lesions (9.5 % were significantly associated with perforation.…”