Tu1108 Inter-Rater Reliability in the Histopathologic Evaluation of Barrett's Esophagus and Associated Neoplasia Among Asian Pathologists

Teh, Ming; Yerian, Lisa; Liu, Xiuli; Cook, Michael B.; Hsu, Chao‐Tien; To, Ka Fai; Shimoda, Tadakazu; Zhou, Cheng-Jun; Chow, Wong‐Ho; Wong, Jennie; Ho, Khek‐Yu

doi:10.1016/s0016-5085(12)62902-3

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Post‐training, the diagnoses made by these pathologists were validated to ensure that an acceptable interrater reliability in the diagnosis of Barrett's esophagus and grading of associated neoplasia had been achieved. The validation found high ICC for the consistency in the rating of both digital histopathology slides (ICC = 0.728; 95% CI 0.653–0.802) and hematoxylin‐eosin‐stained glass slides (ICC = 0.874; 95% CI 0.787–0.943), suggesting excellent interrater reliability in the diagnosis and grading of the disease . The Asia‐Pacific Barrett's Consortium thus upholds the need for both training and standardization of diagnostic criteria for diagnosis and grading of Barrett's esophagus.…”

Section: Training In the Histological Diagnosis Of Barrett's Esophagusmentioning

confidence: 86%

Is Barrett's esophagus an over‐hyped disease in the West, and an underdiagnosed disease in the East?

2013

Digestive Endoscopy

Self Cite

View full text Add to dashboard Cite

Despite the widespread practice of endoscopic surveillance for Barrett's esophagus in the West, this strategy has not been shown to reduce mortality from esophageal adenocarcinoma. Coupled with the very low absolute annual risk of Barrett's adenocarcinoma of 0.1%, this has called into question as to whether Barrett's esophagus is an over‐hyped condition in the West. On the contrary, it is widely assumed that the prevalence of Barrett's esophagus is low in Asia. Could there be under‐recognition of Barrett's esophagus, resulting in the underdiagnosis of the disease in the region? Our own study noted a much higher prevalence of histologically confirmed Barrett's esophagus following increased interest in endoscopic investigation of this disease, suggesting the low prevalence of Barrett's esophagus reported in most parts of Asia could have been attributed, at least in part, to underdiagnosis and/or lack of awareness of the condition. Training in the use of standardized diagnostic criteriacould enhance diagnosis of the disease. In a recent study conducted by the Asia‐Pacific Barrett's Consortium, formal training in the endoscopic recognition of columnar‐lined Barrett's segment enhanced endoscopists' detection of the disease and led to significantly higher diagnostic yield (1.5% vs 0.42% in untrained endoscopists). The use of advanced endoscopic imaging technology such as narrow‐band imaging improved the negative predictive value in the diagnosis of Barrett's esophagus's associated neoplasia. Raman spectroscopy, a novel biomolecular probe‐based technology that does not rely upon operator's interpretation of images, could potentially enhance the detection of Barrett's esophagus and associated neoplasia.

show abstract

Section: Training In the Histological Diagnosis Of Barrett's Esophagusmentioning

confidence: 86%

Tu1108 Inter-Rater Reliability in the Histopathologic Evaluation of Barrett's Esophagus and Associated Neoplasia Among Asian Pathologists

Cited by 1 publication

References 0 publications

Is Barrett's esophagus an over‐hyped disease in the West, and an underdiagnosed disease in the East?

Is Barrett's esophagus an over‐hyped disease in the West, and an underdiagnosed disease in the East?

Contact Info

Product

Resources

About