Tryptophan-Kynurenine Metabolic Pathway and Daytime Dysfunction in Women with HIV
Eran F Shorer,
Leah H Rubin,
Audrey L French
et al.
Abstract:Background.
Sleep disturbances are prevalent in women with HIV (WWH). Tryptophan-kynurenine (T-K) pathway metabolites are associated with alterations in actigraphy derived sleep measures in WWH, although may not always correlate with functional impairment. We investigated the relationship between T-K pathway metabolites and self-reported daytime dysfunction in WWH and women without HIV (WWoH).
Methods.
141 WWH on stable antiretroviral therapy and 140 demographically similar WWoH enrolled in the IDOze Study h… Show more
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