“…Thus, numerous studies perform screening experiments with epimastigotes and/or trypomastigotes further approach the selected active compounds in intracellular amastigotes (e.g. Pizzolatti et al., 2003, Molina-Garza et al., 2014, Legarda-Ceballos et al., 2015, Olivera et al., 2015) or in vivo .…”