Abstract:Abstract-In this correspondence, we show that orthogonal expansions of recurrent signals like electrocardiograms (ECG's) with a reduced number of coefficients is equivalent to a linear time-variant periodic filter. Instantaneous impulse and frequency responses are analyzed for two classical ways of estimating the expansion coefficients: inner product and adaptive estimation with the LMS algorithm. The obtained description as a linear time-variant periodic filter is a useful tool in order to quantify the distor… Show more
“…The number of basis vectors used in the PCR method here was fixed to three which resulted in good noise reduction for all the data. However, it is also possible to adjust the number of basis vectors based on desired frequency-domain characteristics of the denoised signal by using the filter interpretation given in Olmos et al (1999). For heart rate correction of the QT interval, several methods have been proposed.…”
Hypoglycemia is known to affect the repolarization characteristics of the heart, but the mechanisms behind these changes are not completely understood. We analyzed repolarization characteristics continuously from 22 subjects during normoglycemic period, transition period (blood glucose concentration decreasing) and hypoglycemic period from nine healthy controls (Healthy), six otherwise healthy type 1 diabetics (T1DM) and seven type 1 diabetics with disease complications (T1DMc). An advanced principal component regression (PCR)-based method was used for estimating ECG parameters beat-by-beat, and thus, continuous comparison between the repolarization characteristics and blood glucose values was made. We observed that hypoglycemia related ECG changes in the T1DMc group were smaller than changes in the Healthy and T1DM groups. We also noticed that when glucose concentration remained at a low level, the heart rate corrected QT interval prolonged progressively. Finally, a few minutes time lag was observed between the start of hypoglycemia and cardiac repolarization changes. One explanation for these observations could be that hypoglycemia related hormonal changes have a significant role behind the repolarization changes. This could explain at least the observed time lag (hormonal changes are slow) and the lower repolarization changes in the T1DMc group (hormonal secretion lowered in long duration diabetics).
“…The number of basis vectors used in the PCR method here was fixed to three which resulted in good noise reduction for all the data. However, it is also possible to adjust the number of basis vectors based on desired frequency-domain characteristics of the denoised signal by using the filter interpretation given in Olmos et al (1999). For heart rate correction of the QT interval, several methods have been proposed.…”
Hypoglycemia is known to affect the repolarization characteristics of the heart, but the mechanisms behind these changes are not completely understood. We analyzed repolarization characteristics continuously from 22 subjects during normoglycemic period, transition period (blood glucose concentration decreasing) and hypoglycemic period from nine healthy controls (Healthy), six otherwise healthy type 1 diabetics (T1DM) and seven type 1 diabetics with disease complications (T1DMc). An advanced principal component regression (PCR)-based method was used for estimating ECG parameters beat-by-beat, and thus, continuous comparison between the repolarization characteristics and blood glucose values was made. We observed that hypoglycemia related ECG changes in the T1DMc group were smaller than changes in the Healthy and T1DM groups. We also noticed that when glucose concentration remained at a low level, the heart rate corrected QT interval prolonged progressively. Finally, a few minutes time lag was observed between the start of hypoglycemia and cardiac repolarization changes. One explanation for these observations could be that hypoglycemia related hormonal changes have a significant role behind the repolarization changes. This could explain at least the observed time lag (hormonal changes are slow) and the lower repolarization changes in the T1DMc group (hormonal secretion lowered in long duration diabetics).
“…The main advantage of Holter recording over the short-term ECG is that it allows the detection of sporadic events that do not necessarily occur during the few seconds of ECG recording performed in a hospital setting, when the patient is at rest [3][4][5][6] In the case of the recognition of cardiac arrhythmias, the first step is to treat the raw signal coming from an often noisy Holter recording: to filter it to extract the useful signal, to transform it if necessary in the frequency domain or in the domain time scale to locate and segment areas of interest [1].These allow us to quantify and describe each beat. Note that these descriptors are those usually used by the cardiologist to make his diagnosis.…”
This paper tried to address several topics concerning the analysis, synthesis and compression of the electrocardiogram signal (ECG) using the MIT database. We detect the R-wave by identifying the location of each interval delineating a QRS complex using unbiased and biased estimators. In the second part of the work, we segmented the signal into RR periods constituting the vectors of a data matrix, where we extracted its main components in order to reduce the size of the cardiac information, and then further reduced in addition the size by the use of a threshold on the signal. Then the classification is done for automatic detection of heart disease using Support Vector Machine (SVM) and Cuckoo Search Optimized Neural Network. ECG beats with 4 types of abnormalities (RBBB, APC, PVC and LBBB) from ECG records is retrieved from the MIT-BIH arrhythmia database. Analysis of the different groups shows the overall recognition performance was 99.50%. The worst is 99.63% for the RBBB class.
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