True Hermaphroditism

Borup, K

doi:10.3109/00365599609182353

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1999

2023

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Cited by 3 publications

(2 citation statements)

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“… 1 Both müllerian and wolffian structures may be present and the external genitalia are usually atypical, although phenotypically normal males have been identified. 2,3 The degree of masculinization is influenced by the amount of functional testicular tissue. 4 Gonadal composition may be testicular, ovarian or both (ovotestes).…”

Section: Discussionmentioning

confidence: 99%

True hermaphroditism

Walker¹,

Walker²,

Adams

et al. 2000

J Paediatrics Child Health

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Section: Discussionmentioning

confidence: 99%

True hermaphroditism

Walker¹,

Walker²,

Adams

et al. 2000

J Paediatrics Child Health

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“…Its etiology still remains unexplored (1,5). The ovotestis is the most common type of gonad in true hermaphroditism (2), constituting 44% of gonads in a survey of 409 cases reported up to 1981 (6).…”

Section: Discussionmentioning

confidence: 99%

True hermaphroditism associated with microphthalmia

Hayashi

Kageyama²,

Ishizaka³

et al. 1999

European Journal of Endocrinology

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A 4-year-old boy with an undescending left testis, penoscrotal hypospadia and bilateral microphthalmia was admitted to our hospital. Chromosome analysis revealed a karyotype of 46, XX del(x)(p22,31) and the sex-determining region of the Y chromosome (SRY) was negative. The right testis was located in the scrotum and a left cystic ovary-like gonad, a salpinx and a unicorn uterus were found in the left inguinal canal. Histologically the gonad was an ovotestis in which primordial follicles covered infantile seminiferous tubules. Microphthalmia is observed in some congenital syndromes caused by interstitial deletion of the X chromosome. This case suggested that the short arm of the X chromosome was involved in the differentiation of the gonad. Very closely located follicles and infantile seminiferous tubules indicated that induction of meiosis in the fetus was controlled by the local microenvironment in follicles and seminiferous tubules, and not by the systemic hormonal condition.

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