Trophic and maternal transfer of selenium in brown house snakes (Lamprophis fuliginosus)

Hopkins, William A.; Staub, Brandon P.; Baionno, Jennifer A.; Jackson, Brian P.; Roe, John H.; Ford, Neil B.

doi:10.1016/s0147-6513(03)00076-9

Cited by 61 publications

(39 citation statements)

References 29 publications

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“…In the literature, studies on the maternal transfer of Se for reptiles are well documented (Nagle et al, 2001;Hopkins et al, 2004;Roe et al, 2004;Unrine et al, 2006), and present a strong relation between concentration in eggs and concentrations accumulated in female tissue, that is consistent with the results of the present study. Reptilian studies on the remaining elements examined in this study are generally lacking; the only available data come from monitoring studies that only provide contamination in freshly laid eggs, reflecting a potential contamination coming from a maternal transfer (Table 1).…”

Section: Discussionsupporting

confidence: 92%

Maternal transfer of trace elements in leatherback turtles (Dermochelys coriacea) of French Guiana

2008

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a b s t r a c tIn sea turtles, parental investment is limited to the nutrients and energy invested in eggs that will support embryonic development. Leatherback females have the largest clutches with the biggest eggs of the sea turtles and the highest reproductive output in reptiles. The migration between foraging sites and nesting beaches also represents high energy expenditure. The toxicokinetic of pollutants in the tissues is thus expected to vary during those periods but there is a lack of information in reptiles. Concentrations of essential (Copper, Zinc, Selenium) and non-essentials elements (Cadmium, Lead, Mercury) were determined in blood (n = 78) and eggs (n = 76) of 46 free-ranging leatherback females collected in French Guiana. Maternal transfer to eggs and relationships between blood and eggs concentrations during the nesting season were investigated. All trace elements were detectable in both tissues. Levels of toxic metals were lower than essential elements likely due to the high pelagic nature of leatherbacks that seems to limit exposure to toxic elements. Significant relationships between blood and egg concentrations were observed for Se and Cd. Se could have an important role in embryonic development of leatherback turtles and Cd transfer could be linked to similar carrier proteins as Se. Finally, as multiple clutches were sampled from each female, trends in trace elements were investigated along the nesting season. No change was observed in eggs but changes were recorded in blood concentrations of Cu. Cu level decreased while blood Pb levels increased through the nesting season. The high demand on the body during the breeding season seems to affect blood Cu concentrations. Calcium requirement for egg production with concomitant Pb mobilization could explain the increase in blood Pb concentrations along the nesting season.

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Section: Discussionsupporting

confidence: 92%

Maternal transfer of trace elements in leatherback turtles (Dermochelys coriacea) of French Guiana

2008

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“…After careful cleaning and washing to remove external contaminants, trace elements were quantified at the Trace Element Analysis Core (Dartmouth College, Hanover, New Hampshire, USA), using inductively coupled plasma mass spectrometry 11. Toenails were acid digested with Optima nitric acid (Fisher Scientific, St Louis, Missouri, USA) at 105°C followed by the addition of hydrogen peroxide and further heating the dilution with deionised water.…”

Section: Methodsmentioning

confidence: 99%

Pancreatic cancer risk and levels of trace elements

Amaral

Porta

Silverman

et al. 2011

Gut

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103

112

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Background and aims Knowledge on the etiology of exocrine pancreatic cancer (EPC) is scant. The best established risk factor for EPC is tobacco smoking. Among other carcinogens, tobacco contains cadmium, a metal previously associated with an increased risk of EPC. We evaluated the association between concentrations of trace elements in toenails and EPC risk. Methods The study included 118 EPC cases and 399 hospital controls from Eastern Spain. Levels of twelve trace elements were determined in toenail samples by inductively coupled plasma - mass spectrometry. Odds ratios (ORs) and 95% confidence intervals (CIs), adjusted for potential confounders, were calculated using logistic regression. Results Significantly increased risks of EPC were observed among subjects whose concentrations of cadmium (OR=3.58, 95%CI 1.86–6·88; Ptrend=5×10−6), arsenic (OR=2.02, 95%CI 1.08–3.78; Ptrend=0.009), and lead (OR=6.26, 95%CI 2.71–14.47; Ptrend=3×10−5) were in the highest quartile. High concentrations of selenium (OR=0.05, 95%CI 0.02–0.15; Ptrend=8×10−11) and nickel (OR=0.27, 95%CI 0.12–0.59; Ptrend=2×10−4) were inversely associated with risk of EPC. Conclusion We report novel associations of lead, nickel, and selenium toenail concentrations with pancreas cancer risk. Furthermore, results confirm previous associations with cadmium and arsenic. These novel findings, if replicated in independent studies, would point to an important role of trace elements in pancreatic carcinogenesis.

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“…Studies have demonstrated that both essential (e.g., Zn, Se, Cu, and Cr) and non-essential elements (e.g., Cd, Pb, and Hg) are deposited in reptile eggs through maternal transfer (Burger 2002;Guirlet et al 2008;Hopkins et al 2004;Roe et al 2004;Tryfonas et al 2006). In the current study, while concentrations of Cr, Cd, and Pb were low in most of the eggs, Cu was measured in all the eggs evaluated.…”

Section: Maternal Transfer Of Heavy Metalsmentioning

confidence: 99%

Metal accumulation and evaluation of effects in a freshwater turtle

Halbrook

Sparling

et al. 2011

Ecotoxicology

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A variety of contaminants have been detected in aquatic and terrestrial environments around the Paducah Gaseous Diffusion Plant (PGDP), Kentucky. The presence of these contaminants at the PGDP may pose a risk to biota, yet little is known about the bioaccumulation of contaminants and associated effects in wildlife, especially in aquatic turtles. The current study was initiated to evaluate: (1) the accumulation of heavy metals (Cd, Cr, Cu, Pb, and Hg) in aquatic ecosystems associated with the PGDP using red-eared slider turtle (Trachemys scripta elegans) as biomonitors; (2) maternal transfer of heavy metals; and (3) potential hematological and immunological effects resulting from metal accumulation. A total of 26 turtles were collected from 7 ponds located south, adjacent, and north of the PGDP. Liver Cu concentrations were significantly different among ponds and Cu concentrations in eggs were positively correlated with female Cu concentrations in kidney. The concentrations of heavy metals measured in turtle tissues and eggs were low and, based on previous studies of reptiles and established avian threshold levels of heavy metals, did not appear to have adverse effects on aquatic turtles inhabiting ponds near the PGDP. However, total white blood cell counts, heterophil to lymphocyte ratio, and phytohemagglutinin stimulation index were correlated with metal concentrations. Because other factors may affect the hematological and immunological indices, further investigation is needed to determine if these effects are associated with metal exposure, other contaminants, or disease.

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Trophic and maternal transfer of selenium in brown house snakes (Lamprophis fuliginosus)

Cited by 61 publications

References 29 publications

Maternal transfer of trace elements in leatherback turtles (Dermochelys coriacea) of French Guiana

Maternal transfer of trace elements in leatherback turtles (Dermochelys coriacea) of French Guiana

Pancreatic cancer risk and levels of trace elements

Metal accumulation and evaluation of effects in a freshwater turtle

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