tRNA-derived small RNAs in plant response to biotic and abiotic stresses

Abstract

tRNA-derived small RNAs (tsRNAs) represent a novel category of small non-coding RNAs and serve as a new regulator of gene expression at both transcriptional and post-transcriptional levels. Growing evidence indicates that tsRNAs can be induced by diverse stimuli and regulate stress-responsive target genes, allowing plants to adapt to unfavorable environments. Here, we discuss the latest developments about the biogenesis and classification of tsRNAs and highlight the expression regulation and potential function of tsRNAs in plant biotic and abiotic stress responses. Of note, we also collect useful bioinformatics tools and resources for tsRNAs study in plants. Finally, we propose current limitations and future directions for plant tsRNAs research. These recent discoveries have refined our understanding of whether and how tsRNAs enhance plant stress tolerance.

Integrative multi‐omics analysis reveals the crucial biological pathways involved in the adaptive response to NaCl stress in peanut seedlings

“…In addition to biotic stresses, plant growth, development, and crop yield are often limited by abiotic stresses such as nutrient deficiencies, drought, extreme temperatures, soil salinization, and heavy metal contamination (Huang et al, 2023;Luo et al, 2023;Zhou et al, 2023).…”

“…In addition to biotic stresses, plant growth, development, and crop yield are often limited by abiotic stresses such as nutrient deficiencies, drought, extreme temperatures, soil salinization, and heavy metal contamination (Huang et al, 2023; Luo et al, 2023; Zhou et al, 2023). Soil salinization has led to significant crop losses worldwide and is estimated to affect approximately 33% of irrigated farmlands and 1 billion ha of arable land globally (Abbas et al, 2022; Shi et al, 2021; Zhao et al, 2021).…”

Vitamin D-mediated tsRNA-07804 triggers mitochondrial dysfunction and suppresses non-small cell lung cancer progression by targeting CRKL

“…tRNA-derived small RNAs (tsRNAs) represent a novel class of small non-coding RNAs that are vital for protein translation (Wang et al 2023 ). tsRNAs mainly contain tRNA halves (tiRNAs) and tRNA-derived fragments (tRFs) (Li et al 2018 ).…”