Tritium-labelling of Natural Products

Studies on the tritium labelling of some local anaesthetics and amino acids by the microwave discharge modification of the Wilzbach technique

“…Some of them use an external energy source instead of the radiation energy of tritium, such as different types of electric discharges ( 3 , 4. 5 , 6 , ' 9 8 , 9, ' I ) , y-radiation (4), or UV-irradiation (6,10), while others use catalysts ("3 1 3 ) or treat the organic compound adsorbed on charcoal with tritium (14,15). The aim of these modifications was to obtain higher specific activities and/or to decrease the amount of by-products formed in the reaction.…”