Tritiation and characterization of several polyamine natural products

Tritium NMR: A compilation of data and a practical guide

“…Morrison and Filer [ 73 ] performed tritiation and characterization of several tritiated polyamine natural products, including a simplest representative of that class, putrescine, by means of 3 H NMR. Putrescine is a fascinating member of natural products being implicated in the well‐known Alzheimer's disease, cancer, and diabetes and is critical in plant biology, playing a significant role in photosynthesis.…”

“…Tritium proton decoupled NMR spectrum of [ 3 H] putrescine recorded in CD 3 OD at 320 MHz. Reproduced with minor editing privilege from Morrison and Filer [ 73 ] with the permission of Elsevier…”

“…The nearby peak at 3.40 ppm was attributed to a double F I G U R E 5 0 Tritium proton decoupled NMR spectrum of [ 3 H] putrescine recorded in CD 3 OD at 320 MHz. Reproduced with minor editing privilege from Morrison and Filer [73] with the permission of Elsevier F I G U R E 5 1 Tritium proton decoupled NMR spectrum of [ 3 H] dihydrocapsaicin (top) and [N-methyl-3 H] atropine (bottom) recorded in CDCl 3 at 320 MHz. Reproduced with minor editing privilege from Egan et al [74] with the permission of Elsevier labeled tritium species at the same position, with the extra tritium responsible for the slightly upfield chemical shift.…”