Triterpenoids fromSarcopoterium spinosumandSanguisorba minor

Sarcopoterium spinosum extract as an antidiabetic agent: In vitro and in vivo study

“…These diverse activities may be due to several different chemical compounds found in the extract, which act in concert to bring about the antidiabetic effects. Triterpenoid compounds were isolated from Sarcopoterium spinosum extract by Reher et al (1991) and found to have hypoglycemic properties. We identified catechin and epicatechin in the extract.…”

“…Several studies were carried out in the 1960s and 1980s, and showed that Sarcopoterium spinosum root extract exhibits a hypoglycemic effect in rats (Shani et al, 1970). Reher et al isolated and identified three known triterpenoids from the root as the active hypoglycemic substances (Reher et al, 1991). These studies suggest that Sarcopoterium spinosum is an antidiabetic agent.…”

Ethnobotanical studies of <i>Sarcopoterium spinosum</i> in Israel

“…Early publications demonstrated hypoglycemic activity of extracts of the root-bark of S. spinosum by studying diabetic rabbits (Mishinsky et al, 1966;Shani et al, 1970). In order to evaluate its pharmacological activity, experiments on hyperglycemic mice were undertaken (Reher et al, 1991a). In their work of 1991, Reher and coworkers isolated and identified 3 known triterpenoids from the root bark of S. spinosum collected near Istanbul.…”

Anti-diabetic activity of aerial parts of Sarcopoterium spinosum

“…The anti-diabetic activities mentioned in the ethnobotanical literature [5, 6, 13–15], as well as in small experimental studies [16–18], are mostly attributed to the roots of S. spinosum , entailing a significant burden for the potential use of this shrub as a therapeutic agent. The need to uproot the shrub for the preparation of extract might lead to serious ecological and conservational concerns if one suggests harvesting wild plants [19].…”